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      "author": "santano",
      "permlink": "cancer-is-a-curse-but-also-a-growth-market-for-investors",
      "title": "Cancer is a curse, but also a growth market for investors",
      "body": "![20180203_FNP504.jpg](https://steemitimages.com/DQmYQpcYgZgwXwaWmsKwU86iQAqTxFYmyuo43qdU2GwFDU4/20180203_FNP504.jpg)\nCANCER is a grim sort of growth market. By 2030 there will be over 22m new cases a year, up from 14m in 2012, according to the International Agency for Research on Cancer. But as the world marks World Cancer Day, on February 4th, scientists are speaking of a revolution in the battle to beat it. Money managers’ ears have pricked up. Oncology investing is “hot”.\n\nThe most straightforward way to invest in treating cancer is through shares in companies that sell blockbuster drugs. Alternatively, biotech indices track a basket of companies, of which typically 40% are oncology-related. Big Pharma now buys rather than builds much of its innovation. So backing oncology startups can be an especially lucrative (if risky) approach. According to CB Insights, a research firm, equity investment in cancer-therapeutics startups has grown from $2bn in 2013 to $4.5bn in 2017. Take Juno Therapeutics, founded in Seattle in 2013 to develop immunotherapy drugs. It was acquired on January 22nd by Celgene, a Biotech giant, for a whopping $9bn.\n\nEric Schmidt of Cowen, an investment firm, believes that oncology offers “the highest returns on investment of any therapeutic category”. Three developments explain the frenzy. First, demand for cancer treatments is rising as prevalence increases and the world’s middle classes—who can afford insurance—expand. Between 2012 and 2016 the global costs of cancer-related treatments grew from $91bn to $113bn, according to IQVIA, a health-data firm. They are expected to rise to $147bn by 2021.\n\nSecond, scientific progress, particularly around manipulating genes and cells, has been astonishing. The pipeline of oncology drugs in clinical development has expanded by 45% over the past decade. Immuno-oncology (IO), whereby the patient’s own immune system is used to attack cancerous cells, is particularly in vogue. Goldman Sachs, a bank, values the IO market at around $140bn and, despite calling the field “overhyped”, predicts it could grow by another $100bn.\n\nThird, cancer enjoys faster regulatory approvals than other diseases. As Christiana Bardon, of Burrage Capital, puts it, “patients are dying and they are dying now”, so regulatory hurdles are lower.\n\nBut as with any hot commodity, the line between well-founded excitement and unfounded giddiness is thin. Andy Smith, from Edison Investment Research, points out that it is still early days for treatments like CAR-T (a specific type of IO). He worries about an “implied halo”, comparable to the one that now benefits cryptocurrencies. Investments in oncology and in biotech more generally can also resemble cryptocurrencies in their wild price swings (see chart). Another risk is that new treatments, however brilliant, may never be cheap enough to sell. CAR-T could well be game-changing but only a handful of treatments (which cost around $500,000 per patient) have reportedly been sold.\n\nIain Foulkes, director of research at Cancer Research UK (CRUK), a charity, worries that much of the welcome inflow of capital into cancer research is chasing similar opportunities. Rarer types of cancer may get neglected. Partnerships between investors and research institutes can help overcome this. A recently announced tie-up between Merck, a pharmaceutical giant, and CRUK is an example. The drug company will have the right to develop products from any discoveries made; CRUK will share in profits and royalties.\n\nA surge in “ethical” investment, blending financial returns with doing good, will also help. One initiative is a $550m Healthcare Innovations Fund, from Deerfield, an investment firm, a good chunk of the profits from which goes to underserved research areas. Another is a $470m Oncology Impact Fund, raised in 2016 by UBS, a bank, for early-stage oncology research. A sizeable share of the profits go to neglected research areas and to improving access to cancer treatment in poor countries. Already, early successes have allowed the fund to “give back” $2.5m. Its greatest potential lies in future royalties from drugs that make it to market.\n![20180203_FNC692.png](https://steemitimages.com/DQmQeR24HYdP18mgxwhzhfKjsVkCgH1KmzFAsxiX9ifLfts/20180203_FNC692.png)\nMark Haefele of UBS thinks drug companies should consider similar structures. He notes a desire among clients for more than just financial returns. But he adds that it starts with a compelling investment opportunity—and “few fields are as compelling right now as early-stage oncology.”\n\n\nRef  https://www.economist.com/news/finance-and-economics/21736176-progress-developing-treatments-makes-oncology-research-favourite",
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      "title": "Tomato Nutrition May Help You To Fight Cancer and Inflammation",
      "body": "Did you realize that it's accepted more than 7,500 diverse tomato species are developed the world over today? You've most likely heard before that, naturally, tomatoes are really a foods grown from the ground a vegetable. Truth be told, actually they're viewed as a berry, albeit unusually a long-standing United States law going back to the late 1800s arranges them as a vegetable. \n![tomatoes-close-up.jpg](https://steemitimages.com/DQmZZ7HKNBTKUtCbHscqTTTG1XKPSwp5BzpLiftwF4MQPTs/tomatoes-close-up.jpg)\nTomatoes have a long history going back a great many years to around the season of 500 B.C. in Mexico, where they were a staple harvest for the Aztecs and eaten alongside beans and corn. Aztecs and different people groups in the Mesoamerica region utilized the somewhat sweet \"natural product\" in numerous various ways and even held tomatoes in high otherworldly respect — tomato seeds were accepted to be \"honored with forces of divination.\" \n\nTomatoes are one of those simple to-utilize calming foods that fortunately taste extraordinary, as well. As indicated by the Department of Food Sciences at North Carolina State University with respect to an investigation on tomato nourishment, \"Tomatoes are the second most created and expended vegetable across the country and ­are a rich wellspring of lycopene, beta-carotene, folate, potassium, vitamin C, flavonoids, and vitamin E.\" \n\n<h2>Tomato Nutrition Facts</h2>\n\nTomatoes (which have the logical name Solanum lycopersicum) are an individual from the nightshade vegetable family called Solanaceae, which likewise incorporates veggies like peppers, eggplant and potatoes. They are viewed as a high-cell reinforcement food and outstanding amongst other wellsprings of the phytonutrient called lycopene on the planet, which is firmly attached to improved resistance and disease hazard lessening. Albeit a great many people relate lycopene with profoundly hued red tomatoes, it's accepted to show in similarly high amounts in natural yellow, green or orange tomatoes. \n\nLycopene found in tomatoes has very much inquired about advantageous impacts with regards to slowing down dangerous tumor development. Grown-ups with disease who have taken an interest in thinks about ordinarily hint at growth relapse and tumor threat with supplementing with high measurements of lycopene. Research has demonstrated that when lycopene supplements are given to men who as of now have existing prostate malignancy, the lycopene decreases the extent of the tumors and stop the spreading of dangerous cells. \n\nWhile lycopene is most looked into concerning tomato nourishment advantages and prostate disease counteractive action, it's useful for protecting against different sorts, as well. Solid confirmation shows that higher lycopene admission can help secure against lung, stomach, colon, oral, bosom and cervical malignancies. Also, tomatoes supply numerous different types of cell reinforcements and an extensive variety of vitamins, notwithstanding potassium and phosphorus. \n\n1 medium tomato has about: \n\n22 calories \n\n1 gram protein \n\n3 grams sugar \n\n5 grams carbs \n\n1 gram fiber \n\n6 milligrams vitamin C (26 percent DV) \n\n1025 milligrams vitamin A (20 percent DV) \n\n7 milligrams vitamin K (12 percent DV) \n\n292 milligrams potassium (8 percent DV) \n\n1 milligram manganese (7 percent DV) \n\n1 milligram vitamin B6 (5 percent DV) \n\n4 milligrams folate (5 percent DV) \n\n<h2>6 Tomato Nutrition Benefits</h2>\n\n<h3>1. Stacked with Cancer-Fighting Antioxidants</h3>\n\nConcentrates in the course of recent decades have discovered that individuals who eat more tomatoes are more averse to experience the ill effects of prostate disease, which is the most widely recognized type of growth in American men. Cooked tomatoes are particularly useful for battling malignancy on the grounds that once cooked (particularly with a wellspring of fat, similar to olive oil) their rich wellspring of the carotenoid cancer prevention agents called lycopene turns out to be considerably more accessible. \n\nAs a characteristic growth cure, specialists have thought about the invulnerable upgrading impacts of foods containing lycopene for a considerable length of time. Studies going back to the 1990's led by Harvard University Medical School found that men who ate the most tomatoes had a much lower danger of creating prostate disease than non-tomato eaters. A portion of the men were eating as much as 10 servings per week (or more) of tomatoes – including from sources like tomato juice, tomato sauce and crude tomatoes. No less than five examinations bolster a 30 percent to 40 percent lessening in prostate tumor hazard related with high tomato or lycopene utilization. \n\nAs of late a vast report distributed by the Royal Victoria Hospital and McGill University of Montreal explored 11 case-control studies and 10 accomplice considers on the utilization of tomato, tomato items or lycopene for growth counteractive action; they found that tomatoes, particularly when eaten in high sums, offer noteworthy security. \n\nWhat's more lycopene, tomato sustenance contains an assortment of other capable phytochemicals that can help battle across the board interminable sicknesses. For instance, inquire about demonstrates that phenolic acids found in tomatoes can possibly battle lung disease on account of their capacity to repress the development of nitrosamine mixes in the body. \n\n2. Acts as a Natural Anti-Inflammatory\n![inf.jpg](https://steemitimages.com/DQmXBKqnJe4YEPquPvS3iN5dBmvnXWcECZz6z7SEFAvJXtH/inf.jpg)\nTomatoes' profound shading is a decent sign of their high supply of irritation battling cancer prevention agents – which is precisely why numerous sustenance specialists instruct you to \"eat the rainbow.\" Tomatoes are particularly known for having a trio of cell reinforcements called zera-carotene, phytoene and phytofluene that are discovered together in numerous brilliantly hued leafy foods. These are powerful to help to bring down ailment causing aggravation and accordingly moderate age-related illnesses like coronary illness, tumor, diabetes, joint pain and psychological decrease. \n\nOne of the conceivable components for tomatoes' defensive exercises is by \"down-regulation of the incendiary reaction.\" That incorporates repressing expert fiery go betweens, (for example, the lessening of responsive oxygen species), ending genius provocative cytokines from being discharged and changing nitric oxide flag pathways. \n\nIn any case, remember that handling of tomatoes may fundamentally influence the bioavailability of these calming supplements. Homogenization, high warmth treatment/cooking, and the joining of oil in handled tomato items prompts expanded lycopene bioavailability — tragically, in the meantime, these procedures can cause huge misfortunes of other fragile supplements. This is the reason it's a smart thought to eat both crude and cooked tomatoes routinely. \n\n3. Enhances Heart Health \n![hrt.jpg](https://steemitimages.com/DQmcCtQQBbGnYeMRDgDJnvnD1KqZ9iADZ5k4xWsepr8GRnL/hrt.jpg)\nSunflower Heart Disease Icon \n\nTomatoes' cell reinforcements, particularly lycopene, are known to battle free radical harm and along these lines secure the heart against oxidative pressure. This offers assurance identified with coronary illness – which is the main source of death in the U.S and numerous different countries – and brings down the hazard for heart assaults or strokes. A few examinations have discovered that treatment with cancer prevention agent rich tomato concentrate can likewise lessen hypertension, bring down cholesterol normally and enhance vein health. \n\nIn a current report, healthy grown-ups ingesting lycopene as tomato juice, tomato sauce, and delicate gel containers for one week had essentially bring down levels of LDL oxidized cholesterol contrasted and control gatherings. Conceivable components for tomatoes enhancing heart health incorporate upgraded LDL debasement, LDL molecule size and creation, less plaque develop, and changed vein work. \n\nSpecialists comprehend that the numerous supplements found in tomatoes in part work exclusively, yet in addition cooperate from multiple points of view to shield lipoproteins and vascular cells from oxidation. For instance, lutein found in tomatoes can likewise help anticipate or back off the thickening of the courses. \n\nOxidation is the most generally acknowledged hypothesis for the advancement of atherosclerosis, or solidifying and thickening of the supply routes that can prompt cardiovascular ailment. Tomatoes are additionally a decent wellspring of potassium, and can help avert circulatory strain issues because of low potassium admission. \n\n4. Ensures Vision and Eye Health \n![eye-techology-male.jpg](https://steemitimages.com/DQmU3SxjiP4PvWeE3TNud8a1VZa2zEixRGRmjTwBd4HB4Am/eye-techology-male.jpg)\nA defensive compound called lutein is available in tomatoes, and it's extremely healthy for your eyes. Lutein is frequently considered with respect to eye health since it ensures the eye's retina that we requirement for healthy vision. The retina is particularly powerless amid seniority because of long haul harm of UV light radiation and oxidative worry from different elements. Among the numerous carotenoids display in the body, just lutein and zeaxanthin are found in that segment of the eye where light is engaged by the focal point, called the macula lutea. \n\nResearch demonstrates that lutein in tomatoes may act like a characteristic macular degeneration treatment. Remember that macular degeneration is the main source of visual deficiency in more seasoned grown-ups. For individuals not at a high hazard for macular degeneration, eating tomatoes is only a decent method to help enhance vision and forestall waterfalls or general disintegration of fragile eye tissue. \n\n5. Benefits Skin Health \n![skin.jpg](https://steemitimages.com/DQmPePSp78cZt5CWQ9X2rM9z5MVDjd91Gxqow2Dz31upHTC/skin.jpg)\nlovely skin \n\nWith regards to battling skin disease with food, tomatoes ought to be at the highest priority on your rundown. Tomatoes are an incredible vitamin C food, and vitamin C is vital for keeping skin's resistance, flexibility, appearance and composition solid into more seasoned age. One thing to note is that the vitamin C in tomatoes is most amassed in the gel-like substance that encompasses tomato seeds – so be mindful so as not to give this important juice \"a chance to seep out\" excessively and go to squander when cutting tomatoes. \n\nTomatoes' lutein additionally benefits skin health. Lutein is normally present in the skin and creature thinks about have given proof of lutein's noteworthy security against light-prompted skin harm or skin malignancy, particularly from bright wavelengths. \n\n6. Secures Bone Health \n![bone-clipart-1.jpg.png](https://steemitimages.com/DQmc6Dww4zUnSwHZ8SPJKvypDyEwuU79uzebbXE4vL1ZymV/bone-clipart-1.jpg.png)\nhealthy joints and bone health\n\nAs of late lycopene has been connected to better bone health, particularly in elderly individuals. An examination researching the impacts of dietary wellsprings of lycopene in the weight control plans of more seasoned ladies found that the individuals who needed huge lycopene admission were at a higher hazard for bone-related sicknesses and perhaps osteoporosis. \n\nThis is the reason tomatoes and other lycopene-containing foods are prescribed as a component of a hostile to maturing, recuperating diet. Tomatoes are likewise a decent wellspring of supplements like manganese, phosphorus and bone-building vitamin K. \n\nHistory of Tomatoes and Interesting Facts \n\nThe first tomato species initially developed in parts of South America, especially in the Andes Mountains, a large number of years prior. At the time, wild tomatoes seemed lumpier and were not as sweet or smooth as the cutting edge kind. They spread all through the world after the Spanish colonization of the Americas when mariners expedited them back to Europe their boats. \n\nSpanish conquistador Hernán Cortés is accepted to be the first to exchange the little yellow tomato to Europe after he caught the Aztec city of Tenochtitlan, now Mexico City, in 1521. Europeans initially trusted that tomatoes were a kind of eggplant (they weren't far-removed) and partitioned them into sections to be cooked and prepared with salt, dark pepper and oil. After the Spanish colonization of the Americas, the Spanish dispersed tomatoes all through their provinces in the Caribbean and got them to parts Asia, including the Philippines. \n\nThe tomato develops effectively in warm atmospheres, so it spread over the Mediterranean and started generally being developed around the 1540s. The soonest found cookbook with tomato formulas was distributed in Naples, Italy in 1692! In Italy, tomatoes were developed predominantly for designs at first and weren't viewed as a staple food for the regular laborer populace since they were not as filling as different organic products. It took a few hundred years for various sorts of tomato species to show up and for formulas like marinara pasta sauce, pizza and chicken Parmesan to end up well known. \n\nHow do You Buy and Use Tomatoes \n![tom.jpg](https://steemitimages.com/DQmNT7FdKrADnitHPVvgAT1ghF7BpNhHppdGuaSc6jmTpo4/tom.jpg)\nCrisp tomatoes - Dr. Hatchet \n\nToday, tomatoes are a standout amongst the most well-known vegetables (or organic products) developed in the U.S. in individuals' own particular patio nurseries. They even have a notoriety for \"out-creating the necessities of the producers\" since they tend to take off and develop heaps of tomatoes at the same time amid the late spring months. \"Legacy\" tomatoes have particularly turned out to be well known among home plant specialists and natural makers since they arrive in an assortment of splendid hues, fluctuating tastes and sizes. China, India, the U.S and Turkey are the main producers of tomatoes around the world. \n\nSearch for vine-aged tomatoes at agriculturists market or claim to fame stores and in a perfect world pick natural tomatoes when conceivable. Incredibly some examination proposes that a tomato developed in a nursery (or hot-house) has about a large portion of the vitamin C content as its vine-aged cousin! \n\nSo at whatever point conceivable attempt to utilize new brilliantly hued vine-aged tomatoes, which will hold a larger amount of cell reinforcements and supplements. Tomatoes that are prepared to eat ought to be delicate yet at the same time to some degree firm. Typically the milder the get, the riper they are and sweeter they taste. Keep them put away out of the fridge and take a stab at eating them inside a few days of maturing (or make some sauce!) \n\nOn a side note, tomatoes are believed to be one of the foods that individuals infrequently get the opportunity to acknowledge at their pinnacle on the grounds that numerous financially developed tomatoes are picked when under-ready and green and after that made to misleadingly age utilizing nurseries that hold ethylene gas. This may mean your tomato looks ordinary and red when it's accessible for you to buy in supermarkets, however neither will the supplements be the same nor will the taste be tantamount to the genuine article. \n\nKeep in mind that the defensive properties of lycopene, particularly with regards to disease aversion, are most advantageous and absorbable when they're overwhelmed by a fat-rich food. This is the reason it's an incredible plan to eat tomatoes alongside healthy fats like avocado, olive or coconut oil, nuts and seeds, or greasy fish like salmon. Why would that be the situation? Carotenoids are fat-solvent supplements, which implies they get greatest ingestion just when you eat them with a wellspring of common fat. \n\nThis doesn't mean you should make a point to eat oily pizza constantly, be that as it may! It just intends to try including some genuine, oil-based dressing to your plate of mixed greens, or different structures to fat to veggie-based suppers (counting those with verdant greens or cruciferous veggies, which additionally have fat-dissolvable supplements) to support your ingestion. \n\nHealthy Tomato Recipes \n\nYou can utilize a wide range of tomatoes – whether roma, meat steak, cherry or grape – in assorted ways, including eating them crude, adding them to sauces cooked or notwithstanding having some in a juice or smoothie. Tomatoes run awesome with garlic, oil, new herbs of different types (particularly basil and parsley), onions, avocado, peppers, beans and verdant greens. \n\nTomato Basil Juice Recipe \n\nAdd up to Time: 5 minutes \n\nServes: 2 \n\nIngredients: \n\n2 tomatoes \n\n1/2 Cucumber \n\n1 glass new basil \n\nsqueeze of ocean salt \n\nDirections: Add all fixings to vegetable juicer. Tenderly mix squeeze and expend promptly. \n![tom2.jpg](https://steemitimages.com/DQmXSDqaSeMH9XwpnuGYxJcEXWnKkadzDqELToNgHZ4wC8M/tom2.jpg)\nTomato-Basil-Juice \n\nThick Tomato Salsa Recipe \n\nBasil Tomato Pesto Recipe \n\nGarden Squash with Sun-Dried Tomatoes Recipe \n\nPotential Interactions of Eating Tomatoes \n\nIn spite of the fact that tomatoes come stacked with benefits, remember that they are a nightshade vegetable that can disturb health conditions for a few people. Green tomatoes contain a substance called solarnine, which might disturb to individuals with conditions like joint inflammation or some other immune system related maladies. Nightshade vegetables are likewise fairly a typical sensitivity, at any rate with regards to products of the soil. \n\nNumerous health experts board individuals with difficult joint inflammation indications to maintain a strategic distance from nightshades inside and out, albeit some say the advantages of doing this will change a great deal contingent upon somebody's correct resistance – so it isn't generally important to do as such. Tomatoes are likewise generally kept away from by individuals with gerd, or other reflux issue like indigestion in view of their larger amount of corrosive. \n\nOn the off chance that you have heartburn indications or stomach, joint or muscle torment as often as possible, laying off tomatoes may be savvy to test your response. Or then again on the off chance that you encounter unexplained stomach related problems that may recommend a conceivable food affectability, you can have a go at completing an end eat less carbs that removes all nightshade vegetables, including a wide range of tomatoes. These weight control plans are typically most accommodating when you tail them entirely for no less than a month and a half, so despite the fact that this may sound a bit of overwhelming, it's justified regardless of a strive for decreasing further irritation and swelling.",
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