VOTING POWER95.15%
DOWNVOTE POWER0.00%
RESOURCE CREDITS100.00%
REPUTATION PROGRESS56.40%
Net Worth
0.000USD
STEEM
0.000STEEM
SBD
0.000SBD
Own SP
0.000SP
Detailed Balance
| STEEM | ||
| balance | 0.000STEEM | STEEM |
| market_balance | 0.000STEEM | STEEM |
| savings_balance | 0.000STEEM | STEEM |
| reward_steem_balance | 0.000STEEM | STEEM |
| STEEM POWER | ||
| Own SP | 0.000SP | SP |
| Delegated Out | 0.000SP | SP |
| Delegation In | 0.000SP | SP |
| Effective Power | 0.000SP | SP |
| Reward SP (pending) | 0.000SP | SP |
| SBD | ||
| sbd_balance | 0.000SBD | SBD |
| sbd_conversions | 0.000SBD | SBD |
| sbd_market_balance | 0.000SBD | SBD |
| savings_sbd_balance | 0.000SBD | SBD |
| reward_sbd_balance | 0.000SBD | SBD |
{
"balance": "0.000 STEEM",
"savings_balance": "0.000 STEEM",
"reward_steem_balance": "0.000 STEEM",
"vesting_shares": "0.000000 VESTS",
"delegated_vesting_shares": "0.000000 VESTS",
"received_vesting_shares": "0.000000 VESTS",
"sbd_balance": "0.000 SBD",
"savings_sbd_balance": "0.000 SBD",
"reward_sbd_balance": "0.000 SBD",
"conversions": []
}Account Info
| name | migoff |
| id | 617309 |
| rank | 1,913,591 |
| reputation | -5189386677 |
| created | 2018-01-19T10:14:36 |
| recovery_account | steem |
| proxy | None |
| post_count | 2 |
| comment_count | 0 |
| lifetime_vote_count | 0 |
| witnesses_voted_for | 0 |
| last_post | 2018-08-07T13:03:51 |
| last_root_post | 2018-08-07T13:03:51 |
| last_vote_time | 2018-04-28T01:44:30 |
| proxied_vsf_votes | 0, 0, 0, 0 |
| can_vote | 1 |
| voting_power | 9,515 |
| delayed_votes | 0 |
| balance | 0.000 STEEM |
| savings_balance | 0.000 STEEM |
| sbd_balance | 0.000 SBD |
| savings_sbd_balance | 0.000 SBD |
| vesting_shares | 0.000000 VESTS |
| delegated_vesting_shares | 0.000000 VESTS |
| received_vesting_shares | 0.000000 VESTS |
| reward_vesting_balance | 0.000000 VESTS |
| vesting_balance | 0.000 STEEM |
| vesting_withdraw_rate | 0.000000 VESTS |
| next_vesting_withdrawal | 1969-12-31T23:59:59 |
| withdrawn | 80084615 |
| to_withdraw | 80084615 |
| withdraw_routes | 1 |
| savings_withdraw_requests | 0 |
| last_account_recovery | 1970-01-01T00:00:00 |
| reset_account | null |
| last_owner_update | 1970-01-01T00:00:00 |
| last_account_update | 1970-01-01T00:00:00 |
| mined | No |
| sbd_seconds | 31,335,033 |
| sbd_last_interest_payment | 2018-08-07T16:24:39 |
| savings_sbd_last_interest_payment | 1970-01-01T00:00:00 |
{
"id": 617309,
"name": "migoff",
"owner": {
"weight_threshold": 1,
"account_auths": [],
"key_auths": [
[
"STM5QHakbyTvJfpg8m77voP3pNKUkf5NgPrPdDoekBw3Sy8hAhWLs",
1
]
]
},
"active": {
"weight_threshold": 1,
"account_auths": [],
"key_auths": [
[
"STM6YrKn4MfTNbRdXagcwZ4CSh4BmUvRKi9aDVTE1A5kqvd9HyiZL",
1
]
]
},
"posting": {
"weight_threshold": 1,
"account_auths": [],
"key_auths": [
[
"STM534RiicE4t5yWSJSyr4jSbG8DTa5647z8HVLbdBzSp2PyDJam9",
1
]
]
},
"memo_key": "STM78WW3TLmAtnYfD4Qsq6AnQdzHoVY31FkzoAUPZrtZnPapoN1Up",
"json_metadata": "",
"posting_json_metadata": "",
"proxy": "",
"last_owner_update": "1970-01-01T00:00:00",
"last_account_update": "1970-01-01T00:00:00",
"created": "2018-01-19T10:14:36",
"mined": false,
"recovery_account": "steem",
"last_account_recovery": "1970-01-01T00:00:00",
"reset_account": "null",
"comment_count": 0,
"lifetime_vote_count": 0,
"post_count": 2,
"can_vote": true,
"voting_manabar": {
"current_mana": 9515,
"last_update_time": 1524879870
},
"downvote_manabar": {
"current_mana": 0,
"last_update_time": 1516356876
},
"voting_power": 9515,
"balance": "0.000 STEEM",
"savings_balance": "0.000 STEEM",
"sbd_balance": "0.000 SBD",
"sbd_seconds": "31335033",
"sbd_seconds_last_update": "2018-08-09T01:20:54",
"sbd_last_interest_payment": "2018-08-07T16:24:39",
"savings_sbd_balance": "0.000 SBD",
"savings_sbd_seconds": "0",
"savings_sbd_seconds_last_update": "1970-01-01T00:00:00",
"savings_sbd_last_interest_payment": "1970-01-01T00:00:00",
"savings_withdraw_requests": 0,
"reward_sbd_balance": "0.000 SBD",
"reward_steem_balance": "0.000 STEEM",
"reward_vesting_balance": "0.000000 VESTS",
"reward_vesting_steem": "0.000 STEEM",
"vesting_shares": "0.000000 VESTS",
"delegated_vesting_shares": "0.000000 VESTS",
"received_vesting_shares": "0.000000 VESTS",
"vesting_withdraw_rate": "0.000000 VESTS",
"next_vesting_withdrawal": "1969-12-31T23:59:59",
"withdrawn": 80084615,
"to_withdraw": 80084615,
"withdraw_routes": 1,
"curation_rewards": 39,
"posting_rewards": 0,
"proxied_vsf_votes": [
0,
0,
0,
0
],
"witnesses_voted_for": 0,
"last_post": "2018-08-07T13:03:51",
"last_root_post": "2018-08-07T13:03:51",
"last_vote_time": "2018-04-28T01:44:30",
"post_bandwidth": 0,
"pending_claimed_accounts": 0,
"vesting_balance": "0.000 STEEM",
"reputation": -5189386677,
"transfer_history": [],
"market_history": [],
"post_history": [],
"vote_history": [],
"other_history": [],
"witness_votes": [],
"tags_usage": [],
"guest_bloggers": [],
"rank": 1913591
}Withdraw Routes
| Incoming | Outgoing | |
|---|---|---|
Empty |
|
{
"incoming": [],
"outgoing": [
{
"id": 39641,
"from_account": "migoff",
"to_account": "luckdiver",
"percent": 10000,
"auto_vest": false
}
]
}From Date
To Date
2020/01/19 11:25:12
2020/01/19 11:25:12
| parent author | migoff |
| parent permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| author | steemitboard |
| permlink | steemitboard-notify-migoff-20200119t112512000z |
| title | |
| body | Congratulations @migoff! You received a personal award! <table><tr><td>https://steemitimages.com/70x70/http://steemitboard.com/@migoff/birthday2.png</td><td>Happy Birthday! - You are on the Steem blockchain for 2 years!</td></tr></table> <sub>_You can view [your badges on your Steem Board](https://steemitboard.com/@migoff) and compare to others on the [Steem Ranking](https://steemitboard.com/ranking/index.php?name=migoff)_</sub> ###### [Vote for @Steemitboard as a witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1) to get one more award and increased upvotes! |
| json metadata | {"image":["https://steemitboard.com/img/notify.png"]} |
| Transaction Info | Block #40063410/Trx 2fa2a529ee4f55786fcc66ced5b4d1dc21be4392 |
View Raw JSON Data
{
"trx_id": "2fa2a529ee4f55786fcc66ced5b4d1dc21be4392",
"block": 40063410,
"trx_in_block": 18,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2020-01-19T11:25:12",
"op": [
"comment",
{
"parent_author": "migoff",
"parent_permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"author": "steemitboard",
"permlink": "steemitboard-notify-migoff-20200119t112512000z",
"title": "",
"body": "Congratulations @migoff! You received a personal award!\n\n<table><tr><td>https://steemitimages.com/70x70/http://steemitboard.com/@migoff/birthday2.png</td><td>Happy Birthday! - You are on the Steem blockchain for 2 years!</td></tr></table>\n\n<sub>_You can view [your badges on your Steem Board](https://steemitboard.com/@migoff) and compare to others on the [Steem Ranking](https://steemitboard.com/ranking/index.php?name=migoff)_</sub>\n\n\n###### [Vote for @Steemitboard as a witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1) to get one more award and increased upvotes!",
"json_metadata": "{\"image\":[\"https://steemitboard.com/img/notify.png\"]}"
}
]
}2019/01/19 10:52:06
2019/01/19 10:52:06
| parent author | migoff |
| parent permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| author | steemitboard |
| permlink | steemitboard-notify-migoff-20190119t105205000z |
| title | |
| body | Congratulations @migoff! You received a personal award! <table><tr><td>https://steemitimages.com/70x70/http://steemitboard.com/@migoff/birthday1.png</td><td><p>Happy Birthday! - You are on the Steem blockchain for 1 year!<p></td></tr></table> <sub>_[Click here to view your Board](https://steemitboard.com/@migoff)_</sub> > Support [SteemitBoard's project](https://steemit.com/@steemitboard)! **[Vote for its witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1)** and **get one more award**! |
| json metadata | {"image":["https://steemitboard.com/img/notify.png"]} |
| Transaction Info | Block #29590105/Trx 99bac1a3ac1b279d258c2d5420979d34fd246b97 |
View Raw JSON Data
{
"trx_id": "99bac1a3ac1b279d258c2d5420979d34fd246b97",
"block": 29590105,
"trx_in_block": 3,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2019-01-19T10:52:06",
"op": [
"comment",
{
"parent_author": "migoff",
"parent_permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"author": "steemitboard",
"permlink": "steemitboard-notify-migoff-20190119t105205000z",
"title": "",
"body": "Congratulations @migoff! You received a personal award!\n\n<table><tr><td>https://steemitimages.com/70x70/http://steemitboard.com/@migoff/birthday1.png</td><td><p>Happy Birthday! - You are on the Steem blockchain for 1 year!<p></td></tr></table>\n\n<sub>_[Click here to view your Board](https://steemitboard.com/@migoff)_</sub>\n\n\n> Support [SteemitBoard's project](https://steemit.com/@steemitboard)! **[Vote for its witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1)** and **get one more award**!",
"json_metadata": "{\"image\":[\"https://steemitboard.com/img/notify.png\"]}"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/12/31 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/12/31 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #29051047/Virtual Operation #9 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 29051047,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 9,
"timestamp": "2018-12-31T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/12/31 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/12/31 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #29051047/Virtual Operation #8 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 29051047,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 8,
"timestamp": "2018-12-31T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/12/24 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/12/24 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #28849540/Virtual Operation #4 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28849540,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 4,
"timestamp": "2018-12-24T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/12/24 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/12/24 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #28849540/Virtual Operation #3 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28849540,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 3,
"timestamp": "2018-12-24T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/12/17 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/12/17 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #28648074/Virtual Operation #7 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28648074,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 7,
"timestamp": "2018-12-17T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/12/17 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/12/17 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #28648074/Virtual Operation #6 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28648074,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 6,
"timestamp": "2018-12-17T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/12/10 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/12/10 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #28446607/Virtual Operation #6 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28446607,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 6,
"timestamp": "2018-12-10T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/12/10 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/12/10 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #28446607/Virtual Operation #5 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28446607,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 5,
"timestamp": "2018-12-10T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/12/03 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/12/03 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #28245114/Virtual Operation #4 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28245114,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 4,
"timestamp": "2018-12-03T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/12/03 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/12/03 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #28245114/Virtual Operation #3 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28245114,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 3,
"timestamp": "2018-12-03T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/11/26 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/11/26 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #28043589/Virtual Operation #18 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28043589,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 18,
"timestamp": "2018-11-26T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/11/26 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/11/26 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #28043589/Virtual Operation #17 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 28043589,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 17,
"timestamp": "2018-11-26T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/11/19 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/11/19 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #27842091/Virtual Operation #8 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27842091,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 8,
"timestamp": "2018-11-19T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/11/19 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/11/19 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #27842091/Virtual Operation #7 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27842091,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 7,
"timestamp": "2018-11-19T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/11/12 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/11/12 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #27640628/Virtual Operation #5 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27640628,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 5,
"timestamp": "2018-11-12T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/11/12 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/11/12 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #27640628/Virtual Operation #4 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27640628,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 4,
"timestamp": "2018-11-12T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/11/05 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/11/05 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #27439156/Virtual Operation #4 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27439156,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 4,
"timestamp": "2018-11-05T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/11/05 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/11/05 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #27439156/Virtual Operation #3 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27439156,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 3,
"timestamp": "2018-11-05T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/10/29 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/10/29 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #27237731/Virtual Operation #5 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27237731,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 5,
"timestamp": "2018-10-29T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/10/29 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/10/29 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #27237731/Virtual Operation #4 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27237731,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 4,
"timestamp": "2018-10-29T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/10/22 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/10/22 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #27036272/Virtual Operation #8 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27036272,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 8,
"timestamp": "2018-10-22T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/10/22 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/10/22 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #27036272/Virtual Operation #7 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 27036272,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 7,
"timestamp": "2018-10-22T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/10/15 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/10/15 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #26834834/Virtual Operation #7 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 26834834,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 7,
"timestamp": "2018-10-15T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/10/15 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/10/15 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #26834834/Virtual Operation #6 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 26834834,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 6,
"timestamp": "2018-10-15T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffreceived 0.000 STEEM from power down installment (0.000 SP)2018/10/08 17:12:27
migoffreceived 0.000 STEEM from power down installment (0.000 SP)
2018/10/08 17:12:27
| from account | migoff |
| to account | migoff |
| withdrawn | 0.000000 VESTS |
| deposited | 0.000 STEEM |
| Transaction Info | Block #26633372/Virtual Operation #13 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 26633372,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 13,
"timestamp": "2018-10-08T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "migoff",
"withdrawn": "0.000000 VESTS",
"deposited": "0.000 STEEM"
}
]
}migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)2018/10/08 17:12:27
migoffsent 0.003 STEEM to @luckdiver from power down installment (0.004 SP)
2018/10/08 17:12:27
| from account | migoff |
| to account | luckdiver |
| withdrawn | 6.160355 VESTS |
| deposited | 0.003 STEEM |
| Transaction Info | Block #26633372/Virtual Operation #12 |
View Raw JSON Data
{
"trx_id": "0000000000000000000000000000000000000000",
"block": 26633372,
"trx_in_block": 4294967295,
"op_in_trx": 0,
"virtual_op": 12,
"timestamp": "2018-10-08T17:12:27",
"op": [
"fill_vesting_withdraw",
{
"from_account": "migoff",
"to_account": "luckdiver",
"withdrawn": "6.160355 VESTS",
"deposited": "0.003 STEEM"
}
]
}migoffset power down withdrawal route to @luckdiver (100.00%)2018/10/01 17:12:27
migoffset power down withdrawal route to @luckdiver (100.00%)
2018/10/01 17:12:27
| from account | migoff |
| to account | luckdiver |
| percent | 10000 |
| auto vest | false |
| Transaction Info | Block #26431892/Trx 62fb51d2c5698c21177ed5780c345b6c50b6fab5 |
View Raw JSON Data
{
"trx_id": "62fb51d2c5698c21177ed5780c345b6c50b6fab5",
"block": 26431892,
"trx_in_block": 1,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-10-01T17:12:27",
"op": [
"set_withdraw_vesting_route",
{
"from_account": "migoff",
"to_account": "luckdiver",
"percent": 10000,
"auto_vest": false
}
]
}migoffstarted power down of 0.049 SP2018/10/01 17:12:27
migoffstarted power down of 0.049 SP
2018/10/01 17:12:27
| account | migoff |
| vesting shares | 80.084615 VESTS |
| Transaction Info | Block #26431892/Trx 6d00d0fcd4a7c7add5521f8022d2f0e4585f58c2 |
View Raw JSON Data
{
"trx_id": "6d00d0fcd4a7c7add5521f8022d2f0e4585f58c2",
"block": 26431892,
"trx_in_block": 0,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-10-01T17:12:27",
"op": [
"withdraw_vesting",
{
"account": "migoff",
"vesting_shares": "80.084615 VESTS"
}
]
}2018/08/14 07:07:06
2018/08/14 07:07:06
| voter | spaminator |
| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| weight | -29 (-0.29%) |
| Transaction Info | Block #25053863/Trx 47c5766bb900c4a051eb5798c221a5c62d2a7786 |
View Raw JSON Data
{
"trx_id": "47c5766bb900c4a051eb5798c221a5c62d2a7786",
"block": 25053863,
"trx_in_block": 12,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-14T07:07:06",
"op": [
"vote",
{
"voter": "spaminator",
"author": "migoff",
"permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"weight": -29
}
]
}2018/08/14 07:07:03
2018/08/14 07:07:03
| voter | prowler |
| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| weight | -100 (-1.00%) |
| Transaction Info | Block #25053862/Trx 0f73a82c301761fe55e7dd76540a7771250558e7 |
View Raw JSON Data
{
"trx_id": "0f73a82c301761fe55e7dd76540a7771250558e7",
"block": 25053862,
"trx_in_block": 1,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-14T07:07:03",
"op": [
"vote",
{
"voter": "prowler",
"author": "migoff",
"permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"weight": -100
}
]
}migoffsent 0.240 SBD to @avdvla1984- "round"2018/08/09 01:20:54
migoffsent 0.240 SBD to @avdvla1984- "round"
2018/08/09 01:20:54
| from | migoff |
| to | avdvla1984 |
| amount | 0.240 SBD |
| memo | round |
| Transaction Info | Block #24902985/Trx 4c9c04f67b51cb4c025885b4ac4cfcdf0b0f360a |
View Raw JSON Data
{
"trx_id": "4c9c04f67b51cb4c025885b4ac4cfcdf0b0f360a",
"block": 24902985,
"trx_in_block": 25,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-09T01:20:54",
"op": [
"transfer",
{
"from": "migoff",
"to": "avdvla1984",
"amount": "0.240 SBD",
"memo": "round"
}
]
}2018/08/07 21:56:18
2018/08/07 21:56:18
| parent author | migoff |
| parent permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| author | steemitboard |
| permlink | steemitboard-notify-migoff-20180807t215620000z |
| title | |
| body | Congratulations @migoff! You have completed the following achievement on Steemit and have been rewarded with new badge(s) : [](http://steemitboard.com/@migoff) You got a First Vote <sub>_Click on the badge to view your Board of Honor._</sub> <sub>_If you no longer want to receive notifications, reply to this comment with the word_ `STOP`</sub> > Do you like [SteemitBoard's project](https://steemit.com/@steemitboard)? Then **[Vote for its witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1)** and **get one more award**! |
| json metadata | {"image":["https://steemitboard.com/img/notify.png"]} |
| Transaction Info | Block #24870124/Trx 4b647fab5aae71f5d5d83d5fe661b659124adec0 |
View Raw JSON Data
{
"trx_id": "4b647fab5aae71f5d5d83d5fe661b659124adec0",
"block": 24870124,
"trx_in_block": 63,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T21:56:18",
"op": [
"comment",
{
"parent_author": "migoff",
"parent_permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"author": "steemitboard",
"permlink": "steemitboard-notify-migoff-20180807t215620000z",
"title": "",
"body": "Congratulations @migoff! You have completed the following achievement on Steemit and have been rewarded with new badge(s) :\n\n[](http://steemitboard.com/@migoff) You got a First Vote\n\n<sub>_Click on the badge to view your Board of Honor._</sub>\n<sub>_If you no longer want to receive notifications, reply to this comment with the word_ `STOP`</sub>\n\n\n\n> Do you like [SteemitBoard's project](https://steemit.com/@steemitboard)? Then **[Vote for its witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1)** and **get one more award**!",
"json_metadata": "{\"image\":[\"https://steemitboard.com/img/notify.png\"]}"
}
]
}2018/08/07 19:04:39
2018/08/07 19:04:39
| voter | jansher |
| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| weight | 10000 (100.00%) |
| Transaction Info | Block #24866692/Trx da63721ed03e3e7b9a816f064d11933e4c25ef1a |
View Raw JSON Data
{
"trx_id": "da63721ed03e3e7b9a816f064d11933e4c25ef1a",
"block": 24866692,
"trx_in_block": 14,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T19:04:39",
"op": [
"vote",
{
"voter": "jansher",
"author": "migoff",
"permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"weight": 10000
}
]
}2018/08/07 19:04:21
2018/08/07 19:04:21
| voter | akoano |
| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| weight | 10000 (100.00%) |
| Transaction Info | Block #24866686/Trx 2819dcec8d4c9d290dde9f1d92dd3d5e4f3d0b65 |
View Raw JSON Data
{
"trx_id": "2819dcec8d4c9d290dde9f1d92dd3d5e4f3d0b65",
"block": 24866686,
"trx_in_block": 61,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T19:04:21",
"op": [
"vote",
{
"voter": "akoano",
"author": "migoff",
"permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"weight": 10000
}
]
}2018/08/07 19:04:21
2018/08/07 19:04:21
| voter | djmalith |
| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| weight | 10000 (100.00%) |
| Transaction Info | Block #24866686/Trx ac2849e826292c3efcb360b4652b947996c01a83 |
View Raw JSON Data
{
"trx_id": "ac2849e826292c3efcb360b4652b947996c01a83",
"block": 24866686,
"trx_in_block": 60,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T19:04:21",
"op": [
"vote",
{
"voter": "djmalith",
"author": "migoff",
"permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"weight": 10000
}
]
}minnowboostersent 0.004 SBD to @migoff- "You got an upgoat that will be done by jansher,akoano,djmalith. We refund an open value of 0.004 SBD! Request-Id: 1445892"2018/08/07 19:04:21
minnowboostersent 0.004 SBD to @migoff- "You got an upgoat that will be done by jansher,akoano,djmalith. We refund an open value of 0.004 SBD! Request-Id: 1445892"
2018/08/07 19:04:21
| from | minnowbooster |
| to | migoff |
| amount | 0.004 SBD |
| memo | You got an upgoat that will be done by jansher,akoano,djmalith. We refund an open value of 0.004 SBD! Request-Id: 1445892 |
| Transaction Info | Block #24866686/Trx 3da06d7403ae7427623656fe9edca9b448a95c19 |
View Raw JSON Data
{
"trx_id": "3da06d7403ae7427623656fe9edca9b448a95c19",
"block": 24866686,
"trx_in_block": 59,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T19:04:21",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.004 SBD",
"memo": "You got an upgoat that will be done by jansher,akoano,djmalith. We refund an open value of 0.004 SBD! Request-Id: 1445892"
}
]
}migoffsent 0.050 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 19:03:51
migoffsent 0.050 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 19:03:51
| from | migoff |
| to | minnowbooster |
| amount | 0.050 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24866676/Trx 0ea0eb5deacf8c9ddac77421508c420098c09b6a |
View Raw JSON Data
{
"trx_id": "0ea0eb5deacf8c9ddac77421508c420098c09b6a",
"block": 24866676,
"trx_in_block": 1,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T19:03:51",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.050 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}minnowboostersent 0.001 SBD to @migoff- "You got an upgoat that will be done by greenjuice. We refund an open value of 0.001 SBD! Request-Id: 1445855"2018/08/07 18:57:21
minnowboostersent 0.001 SBD to @migoff- "You got an upgoat that will be done by greenjuice. We refund an open value of 0.001 SBD! Request-Id: 1445855"
2018/08/07 18:57:21
| from | minnowbooster |
| to | migoff |
| amount | 0.001 SBD |
| memo | You got an upgoat that will be done by greenjuice. We refund an open value of 0.001 SBD! Request-Id: 1445855 |
| Transaction Info | Block #24866546/Trx 8e3216b2cbe99df78bcfe95edb2a399a3f765fb1 |
View Raw JSON Data
{
"trx_id": "8e3216b2cbe99df78bcfe95edb2a399a3f765fb1",
"block": 24866546,
"trx_in_block": 7,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:57:21",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.001 SBD",
"memo": "You got an upgoat that will be done by greenjuice. We refund an open value of 0.001 SBD! Request-Id: 1445855"
}
]
}2018/08/07 18:57:21
2018/08/07 18:57:21
| voter | greenjuice |
| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| weight | 2900 (29.00%) |
| Transaction Info | Block #24866546/Trx 2f9616f20a315ba05517ff47fb57e08c29a3e633 |
View Raw JSON Data
{
"trx_id": "2f9616f20a315ba05517ff47fb57e08c29a3e633",
"block": 24866546,
"trx_in_block": 5,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:57:21",
"op": [
"vote",
{
"voter": "greenjuice",
"author": "migoff",
"permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"weight": 2900
}
]
}migoffsent 0.100 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 18:56:42
migoffsent 0.100 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 18:56:42
| from | migoff |
| to | minnowbooster |
| amount | 0.100 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24866533/Trx 873dbb38456c5ddbf4ec099dcd091b867122bd4e |
View Raw JSON Data
{
"trx_id": "873dbb38456c5ddbf4ec099dcd091b867122bd4e",
"block": 24866533,
"trx_in_block": 6,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:56:42",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.100 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}minnowboostersent 0.050 SBD to @migoff- "Sorry, we could not upvote you with 0.050 SBD ⇒ $0.075. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445826!."2018/08/07 18:53:27
minnowboostersent 0.050 SBD to @migoff- "Sorry, we could not upvote you with 0.050 SBD ⇒ $0.075. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445826!."
2018/08/07 18:53:27
| from | minnowbooster |
| to | migoff |
| amount | 0.050 SBD |
| memo | Sorry, we could not upvote you with 0.050 SBD ⇒ $0.075. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445826!. |
| Transaction Info | Block #24866468/Trx 1b7ab7bdc2ce03ccf098199484d8c09c3d602f16 |
View Raw JSON Data
{
"trx_id": "1b7ab7bdc2ce03ccf098199484d8c09c3d602f16",
"block": 24866468,
"trx_in_block": 34,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:53:27",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.050 SBD",
"memo": "Sorry, we could not upvote you with 0.050 SBD ⇒ $0.075. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445826!."
}
]
}migoffsent 0.050 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 18:52:54
migoffsent 0.050 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 18:52:54
| from | migoff |
| to | minnowbooster |
| amount | 0.050 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24866457/Trx 5f531cda4350afc59b74d35d57e4bac94d158c4b |
View Raw JSON Data
{
"trx_id": "5f531cda4350afc59b74d35d57e4bac94d158c4b",
"block": 24866457,
"trx_in_block": 3,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:52:54",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.050 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}minnowboostersent 0.150 SBD to @migoff- "Sorry, we could not upvote you with 0.150 SBD ⇒ $0.226. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445739!."2018/08/07 18:41:39
minnowboostersent 0.150 SBD to @migoff- "Sorry, we could not upvote you with 0.150 SBD ⇒ $0.226. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445739!."
2018/08/07 18:41:39
| from | minnowbooster |
| to | migoff |
| amount | 0.150 SBD |
| memo | Sorry, we could not upvote you with 0.150 SBD ⇒ $0.226. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445739!. |
| Transaction Info | Block #24866232/Trx 396b436618f56fa45b996a0b98673a870f887401 |
View Raw JSON Data
{
"trx_id": "396b436618f56fa45b996a0b98673a870f887401",
"block": 24866232,
"trx_in_block": 41,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:41:39",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.150 SBD",
"memo": "Sorry, we could not upvote you with 0.150 SBD ⇒ $0.226. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445739!."
}
]
}migoffsent 0.150 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 18:41:12
migoffsent 0.150 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 18:41:12
| from | migoff |
| to | minnowbooster |
| amount | 0.150 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24866223/Trx ae6a036da3bb6d9a82207ed235a63541d4ad0636 |
View Raw JSON Data
{
"trx_id": "ae6a036da3bb6d9a82207ed235a63541d4ad0636",
"block": 24866223,
"trx_in_block": 4,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:41:12",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.150 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}2018/08/07 18:38:18
2018/08/07 18:38:18
| voter | cannonwar |
| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| weight | 3900 (39.00%) |
| Transaction Info | Block #24866165/Trx 5d46d6054f44b0589cd9563aeee7aba4686ebd75 |
View Raw JSON Data
{
"trx_id": "5d46d6054f44b0589cd9563aeee7aba4686ebd75",
"block": 24866165,
"trx_in_block": 29,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:38:18",
"op": [
"vote",
{
"voter": "cannonwar",
"author": "migoff",
"permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"weight": 3900
}
]
}minnowboostersent 0.004 SBD to @migoff- "You got an upgoat that will be done by cannonwar. We refund an open value of 0.004 SBD! Request-Id: 1445717"2018/08/07 18:38:18
minnowboostersent 0.004 SBD to @migoff- "You got an upgoat that will be done by cannonwar. We refund an open value of 0.004 SBD! Request-Id: 1445717"
2018/08/07 18:38:18
| from | minnowbooster |
| to | migoff |
| amount | 0.004 SBD |
| memo | You got an upgoat that will be done by cannonwar. We refund an open value of 0.004 SBD! Request-Id: 1445717 |
| Transaction Info | Block #24866165/Trx 943d1fdda7e3f31123cc880b8dea0e63e909c835 |
View Raw JSON Data
{
"trx_id": "943d1fdda7e3f31123cc880b8dea0e63e909c835",
"block": 24866165,
"trx_in_block": 22,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:38:18",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.004 SBD",
"memo": "You got an upgoat that will be done by cannonwar. We refund an open value of 0.004 SBD! Request-Id: 1445717"
}
]
}minnowboostersent 0.200 SBD to @migoff- "Sorry, we could not upvote you with 0.200 SBD ⇒ $0.301. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445714!."2018/08/07 18:37:21
minnowboostersent 0.200 SBD to @migoff- "Sorry, we could not upvote you with 0.200 SBD ⇒ $0.301. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445714!."
2018/08/07 18:37:21
| from | minnowbooster |
| to | migoff |
| amount | 0.200 SBD |
| memo | Sorry, we could not upvote you with 0.200 SBD ⇒ $0.301. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445714!. |
| Transaction Info | Block #24866146/Trx 2504f9890843ca554ebdaa773bfbf1c0b55f56cf |
View Raw JSON Data
{
"trx_id": "2504f9890843ca554ebdaa773bfbf1c0b55f56cf",
"block": 24866146,
"trx_in_block": 19,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:37:21",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.200 SBD",
"memo": "Sorry, we could not upvote you with 0.200 SBD ⇒ $0.301. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445714!."
}
]
}migoffsent 0.200 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 18:37:12
migoffsent 0.200 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 18:37:12
| from | migoff |
| to | minnowbooster |
| amount | 0.200 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24866143/Trx 02d90879aed5417136c673e860358a1fb429509d |
View Raw JSON Data
{
"trx_id": "02d90879aed5417136c673e860358a1fb429509d",
"block": 24866143,
"trx_in_block": 17,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:37:12",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.200 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}migoffsent 0.200 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 18:36:42
migoffsent 0.200 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 18:36:42
| from | migoff |
| to | minnowbooster |
| amount | 0.200 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24866133/Trx a5788bf882b4b38b5be2d62b1e82708e31955a21 |
View Raw JSON Data
{
"trx_id": "a5788bf882b4b38b5be2d62b1e82708e31955a21",
"block": 24866133,
"trx_in_block": 12,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:36:42",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.200 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}minnowboostersent 0.200 SBD to @migoff- "Sorry, we could not upvote you with 0.200 SBD ⇒ $0.301. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445684!."2018/08/07 18:34:21
minnowboostersent 0.200 SBD to @migoff- "Sorry, we could not upvote you with 0.200 SBD ⇒ $0.301. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445684!."
2018/08/07 18:34:21
| from | minnowbooster |
| to | migoff |
| amount | 0.200 SBD |
| memo | Sorry, we could not upvote you with 0.200 SBD ⇒ $0.301. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445684!. |
| Transaction Info | Block #24866086/Trx b99dbf6a56a087f8ca4efa37616c730baec3a150 |
View Raw JSON Data
{
"trx_id": "b99dbf6a56a087f8ca4efa37616c730baec3a150",
"block": 24866086,
"trx_in_block": 32,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:34:21",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.200 SBD",
"memo": "Sorry, we could not upvote you with 0.200 SBD ⇒ $0.301. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1445684!."
}
]
}migoffsent 0.200 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 18:33:33
migoffsent 0.200 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 18:33:33
| from | migoff |
| to | minnowbooster |
| amount | 0.200 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24866070/Trx dd88a06f89325f66c848b4b01a301f10765a474e |
View Raw JSON Data
{
"trx_id": "dd88a06f89325f66c848b4b01a301f10765a474e",
"block": 24866070,
"trx_in_block": 64,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T18:33:33",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.200 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}2018/08/07 16:31:00
2018/08/07 16:31:00
| voter | masonmiler |
| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| weight | 10000 (100.00%) |
| Transaction Info | Block #24863619/Trx aeeb5ac747733029a80c09c5dadb5c619aa8a397 |
View Raw JSON Data
{
"trx_id": "aeeb5ac747733029a80c09c5dadb5c619aa8a397",
"block": 24863619,
"trx_in_block": 9,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T16:31:00",
"op": [
"vote",
{
"voter": "masonmiler",
"author": "migoff",
"permlink": "can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments",
"weight": 10000
}
]
}minnowboostersent 0.001 SBD to @migoff- "You got an upgoat that will be done by masonmiler. We refund an open value of 0.001 SBD! Request-Id: 1444960"2018/08/07 16:31:00
minnowboostersent 0.001 SBD to @migoff- "You got an upgoat that will be done by masonmiler. We refund an open value of 0.001 SBD! Request-Id: 1444960"
2018/08/07 16:31:00
| from | minnowbooster |
| to | migoff |
| amount | 0.001 SBD |
| memo | You got an upgoat that will be done by masonmiler. We refund an open value of 0.001 SBD! Request-Id: 1444960 |
| Transaction Info | Block #24863619/Trx 7106f7d9c2364b0b87f8ffbb5c6c850533bc72cb |
View Raw JSON Data
{
"trx_id": "7106f7d9c2364b0b87f8ffbb5c6c850533bc72cb",
"block": 24863619,
"trx_in_block": 7,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T16:31:00",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.001 SBD",
"memo": "You got an upgoat that will be done by masonmiler. We refund an open value of 0.001 SBD! Request-Id: 1444960"
}
]
}migoffsent 0.020 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 16:30:18
migoffsent 0.020 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 16:30:18
| from | migoff |
| to | minnowbooster |
| amount | 0.020 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24863605/Trx 14a6d0d450a9b98452bd650366147e243814a00c |
View Raw JSON Data
{
"trx_id": "14a6d0d450a9b98452bd650366147e243814a00c",
"block": 24863605,
"trx_in_block": 9,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T16:30:18",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.020 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}minnowboostersent 0.150 SBD to @migoff- "Sorry, we could not upvote you with 0.150 SBD ⇒ $0.226. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1444915!."2018/08/07 16:25:27
minnowboostersent 0.150 SBD to @migoff- "Sorry, we could not upvote you with 0.150 SBD ⇒ $0.226. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1444915!."
2018/08/07 16:25:27
| from | minnowbooster |
| to | migoff |
| amount | 0.150 SBD |
| memo | Sorry, we could not upvote you with 0.150 SBD ⇒ $0.226. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1444915!. |
| Transaction Info | Block #24863508/Trx 234a3335939161fb7f555e1d4a28d66ba9e2a23f |
View Raw JSON Data
{
"trx_id": "234a3335939161fb7f555e1d4a28d66ba9e2a23f",
"block": 24863508,
"trx_in_block": 86,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T16:25:27",
"op": [
"transfer",
{
"from": "minnowbooster",
"to": "migoff",
"amount": "0.150 SBD",
"memo": "Sorry, we could not upvote you with 0.150 SBD ⇒ $0.226. Our website https://www.minnowbooster.net has a graph with what sends are currently working, refunding request with id: 1444915!."
}
]
}migoffsent 0.150 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"2018/08/07 16:24:39
migoffsent 0.150 SBD to @minnowbooster- "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
2018/08/07 16:24:39
| from | migoff |
| to | minnowbooster |
| amount | 0.150 SBD |
| memo | https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| Transaction Info | Block #24863492/Trx dd8fbf184cd225ea1329bd5a6d32fc7fc5060560 |
View Raw JSON Data
{
"trx_id": "dd8fbf184cd225ea1329bd5a6d32fc7fc5060560",
"block": 24863492,
"trx_in_block": 15,
"op_in_trx": 0,
"virtual_op": 0,
"timestamp": "2018-08-07T16:24:39",
"op": [
"transfer",
{
"from": "migoff",
"to": "minnowbooster",
"amount": "0.150 SBD",
"memo": "https://steemit.com/news/@migoff/can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments"
}
]
}blackblockchainsent 0.600 SBD to @migoff- "refund"2018/08/07 14:50:03
blackblockchainsent 0.600 SBD to @migoff- "refund"
2018/08/07 14:50:03
| from | blackblockchain |
| to | migoff |
| amount | 0.600 SBD |
| memo | refund |
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2018/08/07 13:03:51
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}migoffpublished a new post: can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments2018/08/07 13:03:51
migoffpublished a new post: can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments
2018/08/07 13:03:51
| parent author | |
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| author | migoff |
| permlink | can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments |
| title | Can scientists leverage mysterious mossy cells for brain disease treatments |
| body | <html> <p>https://cdn.steemitimages.com/DQmXRMuvbpicRvEZ3gfbkk3tvzgMqECRhp2C5b1RgEymk2N/image.png</p> <p><br></p> <p><strong>A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders, according to a study from scientists at the University of North Carolina School of Medicine.</strong></p> <p><br></p> <p>The scientists, who published their work in Neuron, showed that 'mossy cells' in the hippocampus regulate local stem cells to control their production of new neurons, which is important for normal learning and memory, stress response, and mood regulation. Such neurogenesis in the adult brain is disrupted in many common conditions including Alzheimer's disease, depression, anxiety, schizophrenia, traumatic brain injury, and some forms of epilepsy. Targeting mossy cells to reverse such disruption may therefore offer a new strategy for treating these conditions.</p> <p><br></p> <p>'<strong>The hope is we could manipulate even a small number of mossy cells to restore hippocampal neurogenesis and related brain functions</strong>,' said study senior author Juan Song, <code>PhD</code>, assistant professor of pharmacology and member of the UNC Neuroscience Center.</p> <p><br></p> <p>Mossy cells are themselves a type of neuron and live in the part of the hippocampus known as the dentate gyrus, where neural stem cells also reside. These mossy cells -- and the nerve fibers that input various chemical signals to them -- earned their name because their multiple connection points give them a vaguely moss-covered appearance. Their precise functions have long been debated in part because they're not easy to distinguish from other brain cells. But mossy cells are known to be important for learning and memory and unusually sensitive to stresses. They die off quickly, for example, under the low-oxygen conditions of a stroke or heart attack, or when overstimulated by seizures in temporal lobe epilepsy.</p> <p><br></p> <p>Using advanced tracing techniques on several different strains of genetically engineered lab mice, Song and colleagues labeled mossy cells in mouse hippocampi and marked their connections to other brain cells. They found that mossy cells connected to neural stem cells directly and indirectly. These mossy cells directly communicate with stem cells in the hippocampus via an excitatory pathway. The mossy cells also indirectly communicate with stem cells through nearby neurons called interneurons that then connect to stem cells via an inhibitory pathway.</p> <p><br></p> <p>Surprisingly, Song and her team discovered that mossy cells can shift the balance of their direct and indirect signaling, thus dynamically regulating neural stem cell activity. In their experiments, Song's team found that moderate mossy cell activity, for example, resulted in the dominance of indirect signaling and kept stem cells in a '<strong>quiescent</strong>' state that may lead to a low level of neurogenesis, but the stem cells could be preserved over the long term. In contrast, high mossy cell activity, which could occur when the brain is stimulated or in a diseased state, made direct signaling dominant and kept stem cells in an 'activated' state that may lead to a high level of neurogenesis. But this may risk losing stem cells over the long term.</p> <p><br></p> <p>The scientists observed that removing a portion of mossy cells caused neural stem cells to increase their activity briefly followed by a permanent loss of stem cells. The finding hints that the abnormal loss of mossy cells may be a key factor underlying many pathological conditions where neurogenesis is deficient. This suggests replacing or otherwise altering the activity of these mossy cells could be a viable treatment strategy, according to Song.</p> <p><br></p> <p>The experiments also indicated that for mossy cells, a few cells go a long way. In a key set of experiments, the researchers were able to label only about a quarter of the mossy cell population. Yet by manipulating the activity level of these few cells, the scientists observed large changes in hippocampal stem cell activity and neurogenesis.</p> <p><br></p> <p>'<em>We were surprised that this small population of mossy cells could exert such a big impact on stem cell behavior</em>,' Song said.</p> <p><br></p> <p>Song and her team will now make use of the tools and lessons developed in this study to examine what happens to mossy cells in various disease states and how they might be replaced or have their activity altered to treat those diseases.</p> <p><br></p> <p><br></p> </html> |
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"body": "<html> <p>https://cdn.steemitimages.com/DQmXRMuvbpicRvEZ3gfbkk3tvzgMqECRhp2C5b1RgEymk2N/image.png</p> <p><br></p> <p><strong>A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders, according to a study from scientists at the University of North Carolina School of Medicine.</strong></p> <p><br></p> <p>The scientists, who published their work in Neuron, showed that 'mossy cells' in the hippocampus regulate local stem cells to control their production of new neurons, which is important for normal learning and memory, stress response, and mood regulation. Such neurogenesis in the adult brain is disrupted in many common conditions including Alzheimer's disease, depression, anxiety, schizophrenia, traumatic brain injury, and some forms of epilepsy. Targeting mossy cells to reverse such disruption may therefore offer a new strategy for treating these conditions.</p> <p><br></p> <p>'<strong>The hope is we could manipulate even a small number of mossy cells to restore hippocampal neurogenesis and related brain functions</strong>,' said study senior author Juan Song, <code>PhD</code>, assistant professor of pharmacology and member of the UNC Neuroscience Center.</p> <p><br></p> <p>Mossy cells are themselves a type of neuron and live in the part of the hippocampus known as the dentate gyrus, where neural stem cells also reside. These mossy cells -- and the nerve fibers that input various chemical signals to them -- earned their name because their multiple connection points give them a vaguely moss-covered appearance. Their precise functions have long been debated in part because they're not easy to distinguish from other brain cells. But mossy cells are known to be important for learning and memory and unusually sensitive to stresses. They die off quickly, for example, under the low-oxygen conditions of a stroke or heart attack, or when overstimulated by seizures in temporal lobe epilepsy.</p> <p><br></p> <p>Using advanced tracing techniques on several different strains of genetically engineered lab mice, Song and colleagues labeled mossy cells in mouse hippocampi and marked their connections to other brain cells. They found that mossy cells connected to neural stem cells directly and indirectly. These mossy cells directly communicate with stem cells in the hippocampus via an excitatory pathway. The mossy cells also indirectly communicate with stem cells through nearby neurons called interneurons that then connect to stem cells via an inhibitory pathway.</p> <p><br></p> <p>Surprisingly, Song and her team discovered that mossy cells can shift the balance of their direct and indirect signaling, thus dynamically regulating neural stem cell activity. In their experiments, Song's team found that moderate mossy cell activity, for example, resulted in the dominance of indirect signaling and kept stem cells in a '<strong>quiescent</strong>' state that may lead to a low level of neurogenesis, but the stem cells could be preserved over the long term. In contrast, high mossy cell activity, which could occur when the brain is stimulated or in a diseased state, made direct signaling dominant and kept stem cells in an 'activated' state that may lead to a high level of neurogenesis. But this may risk losing stem cells over the long term.</p> <p><br></p> <p>The scientists observed that removing a portion of mossy cells caused neural stem cells to increase their activity briefly followed by a permanent loss of stem cells. The finding hints that the abnormal loss of mossy cells may be a key factor underlying many pathological conditions where neurogenesis is deficient. This suggests replacing or otherwise altering the activity of these mossy cells could be a viable treatment strategy, according to Song.</p> <p><br></p> <p>The experiments also indicated that for mossy cells, a few cells go a long way. In a key set of experiments, the researchers were able to label only about a quarter of the mossy cell population. Yet by manipulating the activity level of these few cells, the scientists observed large changes in hippocampal stem cell activity and neurogenesis.</p> <p><br></p> <p>'<em>We were surprised that this small population of mossy cells could exert such a big impact on stem cell behavior</em>,' Song said.</p> <p><br></p> <p>Song and her team will now make use of the tools and lessons developed in this study to examine what happens to mossy cells in various disease states and how they might be replaced or have their activity altered to treat those diseases.</p> <p><br></p> <p><br></p> </html>",
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2018/08/07 13:02:42
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2018/08/07 12:28:57
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}migoffpublished a new post: can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments2018/08/07 12:28:57
migoffpublished a new post: can-scientists-leverage-mysterious-mossy-cells-for-brain-disease-treatments
2018/08/07 12:28:57
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2018/06/01 15:31:51
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2018/05/15 17:10:54
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2018/05/08 17:10:54
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"weight_threshold": 1,
"account_auths": [],
"key_auths": [
[
"STM6YrKn4MfTNbRdXagcwZ4CSh4BmUvRKi9aDVTE1A5kqvd9HyiZL",
1
]
]
},
"posting": {
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"account_auths": [],
"key_auths": [
[
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1
]
]
},
"memo": "STM78WW3TLmAtnYfD4Qsq6AnQdzHoVY31FkzoAUPZrtZnPapoN1Up"
}Witness Votes
0 / 30
No active witness votes.
[]