{
  "trx_id": "e8aa0dd7e8a718297b4b94bbd72c1d16c6a8b6a1",
  "block": 106140144,
  "trx_in_block": 3,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2026-05-17T21:29:15",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "6915.045346 VESTS"
    }
  ]
}

{
  "trx_id": "e8d1184be5145456d528ab4c05ec82c42a136524",
  "block": 105963908,
  "trx_in_block": 1,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2026-05-11T17:58:33",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "4202.834941 VESTS"
    }
  ]
}

{
  "trx_id": "9da32bdb6df8f17143a319ed3a46e49ea47d4032",
  "block": 105507875,
  "trx_in_block": 1,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2026-04-25T20:54:33",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "6927.561102 VESTS"
    }
  ]
}

{
  "trx_id": "3763b32f0fd9397bcf87df92f4cdfb3b3f170198",
  "block": 102843017,
  "trx_in_block": 4,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2026-01-23T00:27:24",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "4244.381760 VESTS"
    }
  ]
}

{
  "trx_id": "5f391883e04ad9567b883892a66819c11822bd5b",
  "block": 91289452,
  "trx_in_block": 2,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2024-12-16T19:48:00",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "4408.600957 VESTS"
    }
  ]
}

{
  "trx_id": "208f00645f2540c953d1d7bc138ce3f540888f05",
  "block": 79843737,
  "trx_in_block": 3,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2023-11-13T11:34:18",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "4577.734489 VESTS"
    }
  ]
}

{
  "trx_id": "507b3a4005e1049f68710af09613d4706f48a48f",
  "block": 78343964,
  "trx_in_block": 1,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2023-09-21T18:35:42",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "7515.013275 VESTS"
    }
  ]
}

{
  "trx_id": "e804179d5e841dc68d94304895e2c3313d09be92",
  "block": 69109750,
  "trx_in_block": 0,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2022-11-03T08:45:57",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "7736.694713 VESTS"
    }
  ]
}

{
  "trx_id": "c4edd554c74b7dfc704da4853c1e88ae1b0cc7db",
  "block": 60806225,
  "trx_in_block": 1,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2022-01-17T08:16:54",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "7957.227944 VESTS"
    }
  ]
}

{
  "trx_id": "c452ac8242e46d06f8aa39afa7a76e7abf33b5ab",
  "block": 59647879,
  "trx_in_block": 23,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2021-12-07T17:03:57",
  "op": [
    "transfer",
    {
      "from": "antmant",
      "to": "fuadmuhammad",
      "amount": "0.572 SBD",
      "memo": ""
    }
  ]
}

{
  "trx_id": "3b4c65143d25b59651e20e03848dbab998aa79f5",
  "block": 54604748,
  "trx_in_block": 1,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2021-06-13T22:18:54",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "8140.996602 VESTS"
    }
  ]
}

{
  "trx_id": "cceffbcc9addd5cd5dabe5bf39c7495535fa7413",
  "block": 49352312,
  "trx_in_block": 1,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2020-12-11T08:41:24",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "8328.418576 VESTS"
    }
  ]
}

{
  "trx_id": "3db0a449023fea0aa9e4751018d7b8e7f087b13e",
  "block": 49203880,
  "trx_in_block": 6,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2020-12-06T02:18:57",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "1912.543513 VESTS"
    }
  ]
}

{
  "trx_id": "a82cff65bdbfe0bbdcc42a644b167fd298bbdd1f",
  "block": 48907889,
  "trx_in_block": 2,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2020-11-25T15:58:06",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "8345.545193 VESTS"
    }
  ]
}

{
  "trx_id": "331e343ea6b79572687bf34b5d2b9093fa0728e5",
  "block": 43214093,
  "trx_in_block": 17,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2020-05-09T03:13:45",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "8537.431789 VESTS"
    }
  ]
}

{
  "trx_id": "56a26523562372b18802ae39eaa78dc4a4ad0d04",
  "block": 43189746,
  "trx_in_block": 36,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2020-05-08T06:27:09",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "1953.311140 VESTS"
    }
  ]
}

{
  "trx_id": "c85a064988e6791ced50274046497876fa7744e2",
  "block": 39895982,
  "trx_in_block": 4,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2020-01-13T15:37:18",
  "op": [
    "comment",
    {
      "parent_author": "antmant",
      "parent_permlink": "why-we-are-still-hungry",
      "author": "steemitboard",
      "permlink": "steemitboard-notify-antmant-20200113t153718000z",
      "title": "",
      "body": "Congratulations @antmant! You received a personal award!\n\n<table><tr><td>https://steemitimages.com/70x70/http://steemitboard.com/@antmant/birthday2.png</td><td>Happy Birthday! - You are on the Steem blockchain for 2 years!</td></tr></table>\n\n<sub>_You can view [your badges on your Steem Board](https://steemitboard.com/@antmant) and compare to others on the [Steem Ranking](https://steemitboard.com/ranking/index.php?name=antmant)_</sub>\n\n\n###### [Vote for @Steemitboard as a witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1) to get one more award and increased upvotes!",
      "json_metadata": "{\"image\":[\"https://steemitboard.com/img/notify.png\"]}"
    }
  ]
}

{
  "trx_id": "cd31d871b1ddb46139a6f3afcb1f53aec26efce4",
  "block": 34689637,
  "trx_in_block": 8,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2019-07-15T17:31:51",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "8708.696815 VESTS"
    }
  ]
}

{
  "trx_id": "b55327f8672319d25051337aafd915fa6e6672d9",
  "block": 29422705,
  "trx_in_block": 16,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2019-01-13T15:12:45",
  "op": [
    "comment",
    {
      "parent_author": "antmant",
      "parent_permlink": "why-we-are-still-hungry",
      "author": "steemitboard",
      "permlink": "steemitboard-notify-antmant-20190113t151244000z",
      "title": "",
      "body": "Congratulations @antmant! You received a personal award!\n\n<table><tr><td>https://steemitimages.com/70x70/http://steemitboard.com/@antmant/birthday1.png</td><td>1 Year on Steemit</td></tr></table>\n\n<sub>_[Click here to view your Board](https://steemitboard.com/@antmant)_</sub>\n\n\n**Do not miss the last post from @steemitboard:**\n<table><tr><td><a href=\"https://steemit.com/steem/@steemitboard/steemwhales-has-officially-moved-to-steemitboard-ranking\"><img src=\"https://steemitimages.com/64x128/https://cdn.steemitimages.com/DQmfRVpHQhLDhnjDtqck8GPv9NPvNKPfMsDaAFDE1D9Er2Z/header_ranking.png\"></a></td><td><a href=\"https://steemit.com/steem/@steemitboard/steemwhales-has-officially-moved-to-steemitboard-ranking\">SteemWhales has officially moved to SteemitBoard Ranking</a></td></tr><tr><td><a href=\"https://steemit.com/steemitboard/@steemitboard/steemitboard-witness-update-2019-01-07\"><img src=\"https://steemitimages.com/64x128/http://i.cubeupload.com/7CiQEO.png\"></a></td><td><a href=\"https://steemit.com/steemitboard/@steemitboard/steemitboard-witness-update-2019-01-07\">SteemitBoard - Witness Update</a></td></tr></table>\n\n> Support [SteemitBoard's project](https://steemit.com/@steemitboard)! **[Vote for its witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1)** and **get one more award**!",
      "json_metadata": "{\"image\":[\"https://steemitboard.com/img/notify.png\"]}"
    }
  ]
}

{
  "trx_id": "44bfba24a161fd93118bcf8363beedd688799af5",
  "block": 24543442,
  "trx_in_block": 35,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-07-27T13:14:51",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "8907.460915 VESTS"
    }
  ]
}

{
  "trx_id": "a8452fe1b08a554dcc23e2cf848b75a30931445c",
  "block": 22870184,
  "trx_in_block": 43,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-05-30T01:35:48",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "29272.969541 VESTS"
    }
  ]
}

{
  "trx_id": "b303bc90d5179a524d9f2f2d1ac538eba5a762af",
  "block": 21933075,
  "trx_in_block": 22,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-04-27T12:12:54",
  "op": [
    "claim_reward_balance",
    {
      "account": "antmant",
      "reward_steem": "0.000 STEEM",
      "reward_sbd": "0.011 SBD",
      "reward_vests": "6.138193 VESTS"
    }
  ]
}

{
  "trx_id": "26ed65ff96157822356dacfedd7d3b96e5b01475",
  "block": 20289649,
  "trx_in_block": 31,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-03-01T08:51:27",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "ad87a30dc4c692fd21660f97e6e8dba63d0be260",
  "block": 20289646,
  "trx_in_block": 10,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-03-01T08:51:18",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "0000000000000000000000000000000000000000",
  "block": 19464036,
  "trx_in_block": 4294967295,
  "op_in_trx": 0,
  "virtual_op": 9,
  "timestamp": "2018-01-31T16:02:06",
  "op": [
    "author_reward",
    {
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "sbd_payout": "0.011 SBD",
      "steem_payout": "0.000 STEEM",
      "vesting_payout": "6.138193 VESTS"
    }
  ]
}

{
  "trx_id": "35dcb0b3cf698bb9b83f4dda066675536853ba4d",
  "block": 19402452,
  "trx_in_block": 69,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-29T12:39:45",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "jepper",
      "permlink": "if-you-had-to-bet-whether-a-cat-is-right-or-left-handed-would-its-gender-play-a-role",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "8790967754a38a85306728ebb8fb34e7ef9db7c1",
  "block": 19386312,
  "trx_in_block": 6,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-28T23:12:30",
  "op": [
    "custom_json",
    {
      "required_auths": [],
      "required_posting_auths": [
        "antmant"
      ],
      "id": "follow",
      "json": "[\"follow\",{\"follower\":\"antmant\",\"following\":\"jepper\",\"what\":[\"blog\"]}]"
    }
  ]
}

{
  "trx_id": "fbda8fe357f62488703cf3bd2b5ad8f94ef0a791",
  "block": 19367931,
  "trx_in_block": 46,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-28T07:53:09",
  "op": [
    "vote",
    {
      "voter": "jepper",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "b42cf1fea42552a991e62adb66292875fff3cf00",
  "block": 19315752,
  "trx_in_block": 27,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-26T12:22:21",
  "op": [
    "delegate_vesting_shares",
    {
      "delegator": "steem",
      "delegatee": "antmant",
      "vesting_shares": "29476.457423 VESTS"
    }
  ]
}

{
  "trx_id": "293d984ecb2e9d5563b95398c334f22487f67496",
  "block": 19314501,
  "trx_in_block": 9,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-26T11:19:45",
  "op": [
    "claim_reward_balance",
    {
      "account": "antmant",
      "reward_steem": "0.000 STEEM",
      "reward_sbd": "0.515 SBD",
      "reward_vests": "198.521233 VESTS"
    }
  ]
}

{
  "trx_id": "0000000000000000000000000000000000000000",
  "block": 19314093,
  "trx_in_block": 4294967295,
  "op_in_trx": 0,
  "virtual_op": 20,
  "timestamp": "2018-01-26T10:59:15",
  "op": [
    "author_reward",
    {
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "sbd_payout": "0.432 SBD",
      "steem_payout": "0.000 STEEM",
      "vesting_payout": "165.775381 VESTS"
    }
  ]
}

{
  "trx_id": "0000000000000000000000000000000000000000",
  "block": 19312392,
  "trx_in_block": 4294967295,
  "op_in_trx": 0,
  "virtual_op": 5,
  "timestamp": "2018-01-26T09:34:09",
  "op": [
    "author_reward",
    {
      "author": "antmant",
      "permlink": "something-about-me",
      "sbd_payout": "0.083 SBD",
      "steem_payout": "0.000 STEEM",
      "vesting_payout": "32.745852 VESTS"
    }
  ]
}

{
  "trx_id": "1ea6c4b5e85045b1e951af73af9acebe670d0615",
  "block": 19299341,
  "trx_in_block": 5,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T22:41:18",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "title": "The power of our sh*t – how gut microbiota affects our mental health",
      "body": "@@ -141,111 +141,8 @@\n er%3E%0A\n-%3Ccenter%3E%3Ca href=%22https://www.teepublic.com/t-shirt/1018665-get-your-shit-together%22%3ESource%3C/a%3E%3C/center%3E%0A\n %3Cp%3E%3C\n@@ -8103,15 +8103,135 @@\n ant%3C/p%3E%0A\n+%3Ccenter%3E%3Ca href=%22https://www.teepublic.com/t-shirt/1018665-get-your-shit-together%22%3ESource of title picture%3C/a%3E%3C/center%3E%0A\n %3C/html%3E\n",
      "json_metadata": "{\"tags\":[\"steemstem\",\"psychology\",\"science\",\"steemiteducation\",\"health\"],\"image\":[\"https://steemitimages.com/DQmTd1gPpepSFVLriCDSH7yEUuKMkKHHp5X9GtVYS7bNn5o/V%C3%BDst%C5%99i%C5%BEek2.JPG\",\"https://steemitimages.com/DQmZ2SApsdJtDpjabRE5ftCUYQqDWrVXNxoiWmarb1C8qTE/GutMicrobeInfographic.png\",\"https://steemitimages.com/DQmTwdPMbdWQzkvgMsnT3EcZ99RdWiqAqujWsgo8zs9epuh/Gut-Brain_Axis_large.png\"],\"links\":[\"https://drjockers.com/rebuild-gut-flora-metabolism/\",\"https://www.dougcookrd.com/2017/08/gut-brain-mental-health-dietitian/\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662178/\",\"http://www.gutmicrobiotaforhealth.com/en/about-gut-microbiota-info/\",\"https://www.sciencedirect.com/science/article/pii/S2352289516300509\",\"https://www.ncbi.nlm.nih.gov/pubmed/27509521\",\"https://en.wikipedia.org/wiki/Fecal_microbiota_transplant\",\"https://www.teepublic.com/t-shirt/1018665-get-your-shit-together\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "87528e21ac69cffa5d1804206c13fef5f2ea77ab",
  "block": 19299299,
  "trx_in_block": 36,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T22:39:12",
  "op": [
    "transfer",
    {
      "from": "antmant",
      "to": "null",
      "amount": "1.000 SBD",
      "memo": "@antmant/the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health"
    }
  ]
}

{
  "trx_id": "d5a6f9a5317b22e9420200b93237422b5bb7228b",
  "block": 19299249,
  "trx_in_block": 32,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T22:36:42",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "title": "The power of our sh*t – how gut microbiota affects our mental health",
      "body": "@@ -7829,17 +7829,26 @@\n p;%3C/p%3E%0A%3C\n-p\n+h2%3E%3Cstrong\n %3EReferen\n@@ -7853,17 +7853,33 @@\n ences:%3C/\n-p\n+strong%3E %3C/h2\n %3E%0A%3Cp%3Ehtt\n",
      "json_metadata": "{\"tags\":[\"steemstem\",\"psychology\",\"science\",\"steemiteducation\",\"health\"],\"image\":[\"https://steemitimages.com/DQmTd1gPpepSFVLriCDSH7yEUuKMkKHHp5X9GtVYS7bNn5o/V%C3%BDst%C5%99i%C5%BEek2.JPG\",\"https://steemitimages.com/DQmZ2SApsdJtDpjabRE5ftCUYQqDWrVXNxoiWmarb1C8qTE/GutMicrobeInfographic.png\",\"https://steemitimages.com/DQmTwdPMbdWQzkvgMsnT3EcZ99RdWiqAqujWsgo8zs9epuh/Gut-Brain_Axis_large.png\"],\"links\":[\"https://www.teepublic.com/t-shirt/1018665-get-your-shit-together\",\"https://drjockers.com/rebuild-gut-flora-metabolism/\",\"https://www.dougcookrd.com/2017/08/gut-brain-mental-health-dietitian/\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662178/\",\"http://www.gutmicrobiotaforhealth.com/en/about-gut-microbiota-info/\",\"https://www.sciencedirect.com/science/article/pii/S2352289516300509\",\"https://www.ncbi.nlm.nih.gov/pubmed/27509521\",\"https://en.wikipedia.org/wiki/Fecal_microbiota_transplant\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "03c26c56440fff80906cbdf72cc2927dd3556c97",
  "block": 19294600,
  "trx_in_block": 0,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T18:44:15",
  "op": [
    "transfer",
    {
      "from": "blocktrades",
      "to": "antmant",
      "amount": "1.046 SBD",
      "memo": ""
    }
  ]
}

{
  "trx_id": "61aa11adec0bae899de82da9ad90382aac7eb669",
  "block": 19294597,
  "trx_in_block": 19,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T18:44:06",
  "op": [
    "transfer",
    {
      "from": "antmant",
      "to": "blocktrades",
      "amount": "1.208 STEEM",
      "memo": "32492e94-6eca-4b80-846d-1fb83404f2bb"
    }
  ]
}

{
  "trx_id": "6eea8b3698c60ec8e91ba62c8db067b4fe49dd1b",
  "block": 19294498,
  "trx_in_block": 34,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T18:39:09",
  "op": [
    "transfer",
    {
      "from": "blocktrades",
      "to": "antmant",
      "amount": "1.208 STEEM",
      "memo": ""
    }
  ]
}

{
  "trx_id": "35ec4f8e5e01693c726a794a289b5f693c40ad77",
  "block": 19294408,
  "trx_in_block": 14,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T18:34:39",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "title": "The power of our sh*t – how gut microbiota affects our mental health",
      "body": "@@ -137,16 +137,127 @@\n center%3E%0A\n+%3Ccenter%3E%3Ca href=%22https://www.teepublic.com/t-shirt/1018665-get-your-shit-together%22%3ESource%3C/a%3E%3C/center%3E%0A%3Cp%3E%3C/p%3E%0A\n %3Cp%3EWe%C2%B4ve\n@@ -3420,16 +3420,25 @@\n er%3E%0A\n-Source: \n+%3Ccenter%3E%3Ca href=%22\n http\n@@ -3484,16 +3484,37 @@\n abolism/\n+%22%3ESource%3C/a%3E%3C/center%3E\n %0A%3Cp%3E%3C/p%3E\n@@ -4426,16 +4426,132 @@\n center%3E%0A\n+%3Ccenter%3E%3Ca href=%22https://www.dougcookrd.com/2017/08/gut-brain-mental-health-dietitian/%22%3ESource%3C/a%3E%3C/center%3E%0A%3Cp%3E%3C/p%3E%0A\n %3Cp%3EOkay \n",
      "json_metadata": "{\"tags\":[\"steemstem\",\"psychology\",\"science\",\"steemiteducation\",\"health\"],\"image\":[\"https://steemitimages.com/DQmTd1gPpepSFVLriCDSH7yEUuKMkKHHp5X9GtVYS7bNn5o/V%C3%BDst%C5%99i%C5%BEek2.JPG\",\"https://steemitimages.com/DQmZ2SApsdJtDpjabRE5ftCUYQqDWrVXNxoiWmarb1C8qTE/GutMicrobeInfographic.png\",\"https://steemitimages.com/DQmTwdPMbdWQzkvgMsnT3EcZ99RdWiqAqujWsgo8zs9epuh/Gut-Brain_Axis_large.png\"],\"links\":[\"https://www.teepublic.com/t-shirt/1018665-get-your-shit-together\",\"https://drjockers.com/rebuild-gut-flora-metabolism/\",\"https://www.dougcookrd.com/2017/08/gut-brain-mental-health-dietitian/\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662178/\",\"http://www.gutmicrobiotaforhealth.com/en/about-gut-microbiota-info/\",\"https://www.sciencedirect.com/science/article/pii/S2352289516300509\",\"https://www.ncbi.nlm.nih.gov/pubmed/27509521\",\"https://en.wikipedia.org/wiki/Fecal_microbiota_transplant\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "cb470e54ac888a94ebac4a9a347d3d81907bc2de",
  "block": 19294185,
  "trx_in_block": 12,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T18:23:30",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "title": "Science of hunger",
      "body": "@@ -121,16 +121,24 @@\n center%3E%0A\n+%3Ccenter%3E\n %3Ca href=\n@@ -146,128 +146,75 @@\n http\n-s\n ://\n-static1.squarespace.com/static/52f42fd9e4b069d0ed72d8a8/t/582e5cbf5016e1e2d5d27382/1479433412464/%22%3EHyperlink Code%3C/a\n+knowyourmeme.com/photos/1092618-image-macros%22%3ESource%3C/a%3E%3C/center\n %3E%0A%3Cp\n@@ -967,24 +967,32 @@\n ? %3C/p%3E%0A\n+%3Ccenter%3E\n %3Cp%3Ehttps://s\n@@ -1069,32 +1069,203 @@\n BD.JPG %3C/p%3E\n+%3C/center%3E%0A%3Ccenter%3E%3Ca href=%22http://www.evolvenutritionaltherapy.com/eat-to-evolve-blog/2016/11/17/your-hormonal-optimization-cheat-sheet-part-2%22%3ESource%3C/a%3E%3C/center%3E%0A%3Cp%3E%3C/p%3E\n %0A%3Ch2%3E &nbsp\n@@ -1308,24 +1308,32 @@\n  %3C/h2%3E%0A\n+%3Cp%3E%3C/p%3E%0A\n %3Cp%3EI tell yo\n@@ -3300,16 +3300,24 @@\n p;%3C/h2%3E%0A\n+%3Cp%3E%3C/p%3E%0A\n %3Cp%3EDurin\n@@ -3837,16 +3837,24 @@\n p;%3C/h2%3E%0A\n+%3Cp%3E%3C/p%3E%0A\n %3Cp%3EWe ea\n@@ -6625,16 +6625,24 @@\n on.%3C/p%3E%0A\n+%3Ccenter%3E\n %3Cp%3Ehttps\n@@ -6778,24 +6778,132 @@\n 14be.gif%3C/p%3E\n+%3C/center%3E%0A%3Ccenter%3E%3Ca href=%22https://www.theodysseyonline.com/dumbledore-terrible%22%3ESource%3C/a%3E%3C/center%3E%0A%3Cp%3E%3C/p%3E\n %0A%3Cp%3ESo if yo\n@@ -7418,20 +7418,66 @@\n p%3E%0A%3C\n-p%3EResources:\n+h2%3E  %3Cstrong%3EReferences:%3C/strong%3E %3C/h2%3E%0A%3Cp%3E\n %3C/p%3E\n@@ -7894,17 +7894,38 @@\n %3C/p%3E%0A%3Cp%3E\n-R\n+Something more about r\n eversion\n",
      "json_metadata": "{\"tags\":[\"steemstem\",\"steemiteducation\",\"science\",\"health\",\"education\"],\"image\":[\"https://steemitimages.com/DQmQR69huGa2yimNnK3QXTLzuTp4AWCGwdUpnx49hCBsJwK/hngr%20ott%20small.JPG\",\"https://steemitimages.com/DQmZxbK5knNRSi3MzaMGq62cUh3rKdqgQ1ycSC69PVjqaj1/V%C3%BD.JPG\",\"https://steemitimages.com/DQmWCbahNXRyT5iELEwcCZQSGssTzac3aWLMqa5hEWzWJnq/c1cc4718b2a07681a4c4b34a09ef879c32871c5c495c638cb775a6b0143014be.gif\"],\"links\":[\"http://knowyourmeme.com/photos/1092618-image-macros\",\"http://www.evolvenutritionaltherapy.com/eat-to-evolve-blog/2016/11/17/your-hormonal-optimization-cheat-sheet-part-2\",\"https://www.theodysseyonline.com/dumbledore-terrible\",\"https://en.wikipedia.org/wiki/Ghrelin\",\"https://en.wikipedia.org/wiki/Insulin\",\"https://en.wikipedia.org/wiki/Leptin\",\"http://www.pnas.org/content/115/2/427.full\",\"https://www.ncbi.nlm.nih.gov/pubmed/17339026\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "256153bddcf702141bcf981648118c7e706fecc1",
  "block": 19293673,
  "trx_in_block": 44,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T17:57:51",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "title": "Science of hunger",
      "body": "@@ -1,15 +1,23 @@\n %3Chtml%3E%0A\n+%3Ccenter%3E\n %3Cp%3Ehttps\n@@ -107,24 +107,176 @@\n mall.JPG%3C/p%3E\n+%3C/center%3E%0A%3Ca href=%22https://static1.squarespace.com/static/52f42fd9e4b069d0ed72d8a8/t/582e5cbf5016e1e2d5d27382/1479433412464/%22%3EHyperlink Code%3C/a%3E%0A%3Cp%3E%3C/p%3E\n %0A%3Cp%3EProbably\n@@ -1108,160 +1108,8 @@\n .JPG\n-%3C/p%3E%0A%3Cp%3E <a href=%22https://static1.squarespace.com/static/52f42fd9e4b069d0ed72d8a8/t/582e5cbf5016e1e2d5d27382/1479433412464/%22>Source</a>\n &nbs\n",
      "json_metadata": "{\"tags\":[\"steemstem\",\"steemiteducation\",\"science\",\"health\",\"education\"],\"image\":[\"https://steemitimages.com/DQmQR69huGa2yimNnK3QXTLzuTp4AWCGwdUpnx49hCBsJwK/hngr%20ott%20small.JPG\",\"https://steemitimages.com/DQmZxbK5knNRSi3MzaMGq62cUh3rKdqgQ1ycSC69PVjqaj1/V%C3%BD.JPG\",\"https://steemitimages.com/DQmWCbahNXRyT5iELEwcCZQSGssTzac3aWLMqa5hEWzWJnq/c1cc4718b2a07681a4c4b34a09ef879c32871c5c495c638cb775a6b0143014be.gif\"],\"links\":[\"https://static1.squarespace.com/static/52f42fd9e4b069d0ed72d8a8/t/582e5cbf5016e1e2d5d27382/1479433412464/\",\"https://en.wikipedia.org/wiki/Ghrelin\",\"https://en.wikipedia.org/wiki/Insulin\",\"https://en.wikipedia.org/wiki/Leptin\",\"http://www.pnas.org/content/115/2/427.full\",\"https://www.ncbi.nlm.nih.gov/pubmed/17339026\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "b2665e473c33918d5561a77cfbfa8effb17b0462",
  "block": 19293632,
  "trx_in_block": 15,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T17:55:48",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "title": "Science of hunger",
      "body": "@@ -5,24 +5,9 @@\n l%3E%0A%3C\n-h2%3E%3C/h2%3E%0A%3Ccenter\n+p\n %3Ehtt\n@@ -97,37 +97,24 @@\n 0small.JPG%3C/\n-center%3E%0A%3Cp%3E%3C/\n p%3E%0A%3Cp%3EProbab\n@@ -853,30 +853,25 @@\n  %3C/p%3E%0A%3C\n-center\n+p\n %3Ehttps://ste\n@@ -946,27 +946,172 @@\n BD.JPG%3C/\n-center%3E%0A%3Cp%3E\n+p%3E%0A%3Cp%3E <a href=%22https://static1.squarespace.com/static/52f42fd9e4b069d0ed72d8a8/t/582e5cbf5016e1e2d5d27382/1479433412464/%22>Source</a> \n %3C/p%3E%0A%3Ch2\n@@ -1166,32 +1166,24 @@\n  %3C/h2%3E%0A\n-%3Cp%3E%3C/p%3E%0A\n %3Cp%3EI tell yo\n@@ -3150,24 +3150,16 @@\n p;%3C/h2%3E%0A\n-%3Cp%3E%3C/p%3E%0A\n %3Cp%3EDurin\n@@ -3679,24 +3679,16 @@\n p;%3C/h2%3E%0A\n-%3Cp%3E%3C/p%3E%0A\n %3Cp%3EWe ea\n@@ -4927,24 +4927,16 @@\n p;%3C/h2%3E%0A\n-%3Cp%3E%3C/p%3E%0A\n %3Cp%3EIn th\n@@ -6460,22 +6460,17 @@\n n.%3C/p%3E%0A%3C\n-center\n+p\n %3Ehttps:/\n@@ -6610,21 +6610,8 @@\n if%3C/\n-center%3E%0A%3Cp%3E%3C/\n p%3E%0A%3C\n",
      "json_metadata": "{\"tags\":[\"steemstem\",\"steemiteducation\",\"science\",\"health\",\"education\"],\"image\":[\"https://steemitimages.com/DQmQR69huGa2yimNnK3QXTLzuTp4AWCGwdUpnx49hCBsJwK/hngr%20ott%20small.JPG\",\"https://steemitimages.com/DQmZxbK5knNRSi3MzaMGq62cUh3rKdqgQ1ycSC69PVjqaj1/V%C3%BD.JPG\",\"https://steemitimages.com/DQmWCbahNXRyT5iELEwcCZQSGssTzac3aWLMqa5hEWzWJnq/c1cc4718b2a07681a4c4b34a09ef879c32871c5c495c638cb775a6b0143014be.gif\"],\"links\":[\"https://static1.squarespace.com/static/52f42fd9e4b069d0ed72d8a8/t/582e5cbf5016e1e2d5d27382/1479433412464/\",\"https://en.wikipedia.org/wiki/Ghrelin\",\"https://en.wikipedia.org/wiki/Insulin\",\"https://en.wikipedia.org/wiki/Leptin\",\"http://www.pnas.org/content/115/2/427.full\",\"https://www.ncbi.nlm.nih.gov/pubmed/17339026\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "7b3f7cc47e8c424c6554f5c1542a911f6fbb4674",
  "block": 19289871,
  "trx_in_block": 32,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T14:47:42",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "cottonlazarus",
      "permlink": "astronomy-picture-of-the-day-collision-of-two-galaxies",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "081ac74697a8d51bfd7ec0e46c73a9059244b739",
  "block": 19274211,
  "trx_in_block": 24,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-25T01:44:18",
  "op": [
    "vote",
    {
      "voter": "mavedanal",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "bd37bffbd91a4101328e71fd2d4b59fec8ae9f60",
  "block": 19267610,
  "trx_in_block": 19,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-24T20:14:09",
  "op": [
    "vote",
    {
      "voter": "bewise",
      "author": "antmant",
      "permlink": "something-about-me",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "2139bc81dfccbf7022390b64595b1309a60613a8",
  "block": 19267607,
  "trx_in_block": 31,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-24T20:14:00",
  "op": [
    "vote",
    {
      "voter": "bewise",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "9023e0770ab873bc4ad7b0aa859bbc8be3723792",
  "block": 19264169,
  "trx_in_block": 13,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-24T17:22:03",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "title": "Science of hunger",
      "body": "<html>\n<h2></h2>\n<center>https://steemitimages.com/DQmQR69huGa2yimNnK3QXTLzuTp4AWCGwdUpnx49hCBsJwK/hngr%20ott%20small.JPG</center>\n<p></p>\n<p>Probably you know this. You stand on scale and... oh sh*t. What is your first thought? I start excercise! Okay. I start eat less. Cool. But brave promises are easy with full stomach. Self-discipline is tried, when hunger comes. And then we start eat. And that´s good, because we have to. Any diet based on extreme food deprivation is WRONG, because we need adequate amount of food – but nowadays in the era of full fridges and shelves we just forgot how much we need food. So before we start eating we have to consider and control two things. WHAT we eat and HOW MUCH is enough. But HOW do we know HOW MUCH is enough... when we are still hungry, but we have still too much fat storages?! What hunger is and how is it created in our brain?&nbsp;</p>\n<center>https://steemitimages.com/DQmZxbK5knNRSi3MzaMGq62cUh3rKdqgQ1ycSC69PVjqaj1/V%C3%BD.JPG</center>\n<p></p>\n<h2>&nbsp;&nbsp;<strong>What holds us back</strong>&nbsp;</h2>\n<p></p>\n<p>I tell you a story about what is happening when we are hungry. Our stomach is empty and it shrinks. Subesquently <strong>ghrelin,</strong> called also „hunger hormone“, is secreted. Ghrelin starts to bind to receptors in our brain and brain starts yelling stupid ideas: „I´m hungry! Eat that cake! It´s fast source of energy!“ And of course we eat it and we are grumbling with full mouth about how we can start tommorow. But story continues... &nbsp;</p>\n<p>Our digestive enzymes dissolve macronutrients in cake mostly on glucosis and through intestine wall is glucosis absobed to blood. But glucosis can´t stay in blood forever – if it happens, for example during diabetes, it causes a lot of health problems. But in healthy body we have some receptors or sensors of glucosis level in the blood – beta cells in pancreas. They reacts on high glucosis level in blood by excretion of <strong>insulin</strong>. And what is function of insulin? The thing is, glucosis on it´s own can´t be absorbed by cells – so insulin helps to enter glucosis into the cells. If we go running after sweet pleasure, insulin with hands full of glucosis is knocking on muscle cell´s doors and we are burning recieved energy. If we are sitting and resting, it´s quite more difficult situation. Our basal metabolism (mostly brain, but also muscles, organs etc.) consume some portion of this energy, but when it´s too much, insulin starts to knock on to liver, where excesive energy is stored (as glycogen) for bad times. But liver is not bottomless well of course. When it´s full, insulin starts with storing energy for very bad times. To fat. If the cakes (or any other kind food which amount exceed caloric intake/expenditure) were already some, and this is your routine for a few days/weeks/months (based on your metabolism) and you are not a bear preparing on a winter (based on actual season), you have a problem.&nbsp;</p>\n<h2>&nbsp;&nbsp;<strong>Okay we got fat - what next?</strong>&nbsp;</h2>\n<p></p>\n<p>During some time of hedonistic eating or few dozens small sins our fat storages are slowly expanded, but nothing is lost yet. It´s time for <strong>leptin</strong>, produced by fat tissue. Basically, more fat we gain, more leptin is generated. It has also receptors in brain and when fat tissue is gaining weight under our skin, our brain starts to give us a good advice – „Okay, this was last bite, we have enough!“ And our appetite is decreased.&nbsp;</p>\n<h2>&nbsp;&nbsp;<strong>When things go wrong...</strong>&nbsp;</h2>\n<p></p>\n<p>We eat, but ghrelin is still high and we are still hungry. Levels of insulin and glucosis are beyond the normal values, but cells are without energy and we are tired (maybe winter´s comming). Fat is too much, leptin is pouring from our ears, but our brain is telling us to eat even a plate.&nbsp;</p>\n<p>Imagine that your phone is ringing. You answer, don´t you? Exspecially, when you see the name of person you know. What happens if he/she starts to call more often? Few times you pick up the phone because you were well-behaved, but if this person is still calling, it starts to bother you. Phone is ringing every moment and you´re loosing your mind. After few calls you stop answer, start ignore it and probably even turn down volume of your phone.&nbsp;</p>\n<p>And this example ilustrates the problem of resistance. If the cells are constantly shooted by „ringing“ of this hormones, they adapt and start ignore these signals. And we´re gaining fat. It´s important to note, if we start solve these problems with maintaining of our diet plan and excercising they´re reversible in the begining (more info in the resources).&nbsp;</p>\n<h2>&nbsp;&nbsp;<strong>Mice with backpacks, without bones... enough internet for today. </strong>&nbsp;</h2>\n<p></p>\n<p>In the beginning of this year a new mechanism of maintaining weight was discovered. First was the question – why people with sedentary lifestyle are prone to gaining weight, even when all hormonal mechanisms mentioned above are working properly? It was hypothesised, there is other mechanism connected with standing. What (or where) is difference between standing and sitting?&nbsp;</p>\n<p>For revealing the truth, mice was used once again. Scientists implanted them weights with different weight under their skin in abdomen or back and give them free amount of food. Surprisingly, mice with weights started to eat less in compare with mice without weights, and subsequently they lost fat. But this wasn´t end. Scientists are scientist because they often ask <em>„why?“</em>. Based on the assumption that osteocytes (type of bone cells) can detect changes of body weight, they started to suspect bones as participants in this mechanism. They depleted osteocytes in mice and effect of loosing weight by carrying weights disappeared. This newly revealed mechanism was called „gravitostat“. As every homeostatic mechanism, it has to have some sensor, and based on this findings, this sensor is located in bones of lower extremities bearing whole body weight. If this mechanism is presented in humans, strained osteocytes in leg bones inform brain about changes of weight and it regulates this changes by negative feedback through maintaining of food intake. So it seems, gravitostat is cooperating with leptin on fat reduction.</p>\n<center>https://steemitimages.com/DQmWCbahNXRyT5iELEwcCZQSGssTzac3aWLMqa5hEWzWJnq/c1cc4718b2a07681a4c4b34a09ef879c32871c5c495c638cb775a6b0143014be.gif</center>\n<p></p>\n<p>So if you have problems with loosing weight, but you eat well and excercise regularly, probably you should think about that what are you doing during the rest of the day. Of course we all have a lot of responsibilities at work or at school, where we have to sit. But maybe isn´t bad idea to use stairs even we have elevator in the building, or make a few steps after lunch. So if you are finished with this article, take a small walk and stimulate your gravitostat. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>\n<p><br></p>\n<p>Resources:</p>\n<p><a href=\"https://en.wikipedia.org/wiki/Ghrelin\">https://en.wikipedia.org/wiki/Ghrelin</a></p>\n<p><a href=\"https://en.wikipedia.org/wiki/Insulin\">https://en.wikipedia.org/wiki/Insulin</a>&nbsp;</p>\n<p><a href=\"https://en.wikipedia.org/wiki/Leptin\">https://en.wikipedia.org/wiki/Leptin</a>&nbsp;</p>\n<p><a href=\"http://www.pnas.org/content/115/2/427.full\">http://www.pnas.org/content/115/2/427.full</a>&nbsp;</p>\n<p>Reversion of hormone resistance:</p>\n<p><a href=\"https://www.ncbi.nlm.nih.gov/pubmed/17339026\">https://www.ncbi.nlm.nih.gov/pubmed/17339026</a>&nbsp;</p>\n<p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/\">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/</a> &nbsp;&nbsp;&nbsp;</p>\n</html>",
      "json_metadata": "{\"tags\":[\"steemstem\",\"steemiteducation\",\"science\",\"health\",\"education\"],\"image\":[\"https://steemitimages.com/DQmQR69huGa2yimNnK3QXTLzuTp4AWCGwdUpnx49hCBsJwK/hngr%20ott%20small.JPG\",\"https://steemitimages.com/DQmZxbK5knNRSi3MzaMGq62cUh3rKdqgQ1ycSC69PVjqaj1/V%C3%BD.JPG\",\"https://steemitimages.com/DQmWCbahNXRyT5iELEwcCZQSGssTzac3aWLMqa5hEWzWJnq/c1cc4718b2a07681a4c4b34a09ef879c32871c5c495c638cb775a6b0143014be.gif\"],\"links\":[\"https://en.wikipedia.org/wiki/Ghrelin\",\"https://en.wikipedia.org/wiki/Insulin\",\"https://en.wikipedia.org/wiki/Leptin\",\"http://www.pnas.org/content/115/2/427.full\",\"https://www.ncbi.nlm.nih.gov/pubmed/17339026\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "d72cd0a3a45964205308f90f0f8eee3c707e7bdc",
  "block": 19262570,
  "trx_in_block": 28,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-24T16:02:06",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "why-we-are-still-hungry",
      "title": "Why we are (still) hungry?!",
      "body": "<html>\n<h2></h2>\n<center>https://steemitimages.com/DQmQR69huGa2yimNnK3QXTLzuTp4AWCGwdUpnx49hCBsJwK/hngr%20ott%20small.JPG</center>\n<p></p>\n<p>Probably you know this. You stand on scale and... oh sh*t. What is your first thought? I start excercise! Okay. I start eat less. Cool. But brave promises are easy with full stomach. Self-discipline is tried, when hunger comes. And then we start eat. And that´s good, because we have to. Any diet based on extreme food deprivation is WRONG, because we need adequate amount of food – but nowadays in the era of full fridges and shelves we just forgot how much we need food. So before we start eating we have to consider and control two things. WHAT we eat and HOW MUCH is enough. But HOW do we know HOW MUCH is enough... when we are still hungry, but we have still too much fat storages?! What hunger is and how is it created in our brain?&nbsp;</p>\n<center>https://steemitimages.com/DQmZxbK5knNRSi3MzaMGq62cUh3rKdqgQ1ycSC69PVjqaj1/V%C3%BD.JPG</center>\n<p></p>\n<h2>&nbsp;&nbsp;<strong>What holds us back</strong>&nbsp;</h2>\n<p></p>\n<p>I tell you a story about what is happening when we are hungry. Our stomach is empty and it shrinks. Subesquently <strong>ghrelin,</strong> called also „hunger hormone“, is secreted. Ghrelin starts to bind to receptors in our brain and brain starts yelling stupid ideas: „I´m hungry! Eat that cake! It´s fast source of energy!“ And of course we eat it and we are grumbling with full mouth about how we can start tommorow. But story continues... &nbsp;</p>\n<p>Our digestive enzymes dissolve macronutrients in cake mostly on glucosis and through intestine wall is glucosis absobed to blood. But glucosis can´t stay in blood forever – if it happens, for example during diabetes, it causes a lot of health problems. But in healthy body we have some receptors or sensors of glucosis level in the blood – beta cells in pancreas. They reacts on high glucosis level in blood by excretion of <strong>insulin</strong>. And what is function of insulin? The thing is, glucosis on it´s own can´t be absorbed by cells – so insulin helps to enter glucosis into the cells. If we go running after sweet pleasure, insulin with hands full of glucosis is knocking on muscle cell´s doors and we are burning recieved energy. If we are sitting and resting, it´s quite more difficult situation. Our basal metabolism (mostly brain, but also muscles, organs etc.) consume some portion of this energy, but when it´s too much, insulin starts to knock on to liver, where excesive energy is stored (as glycogen) for bad times. But liver is not bottomless well of course. When it´s full, insulin starts with storing energy for very bad times. To fat. If the cakes (or any other kind food which amount exceed caloric intake/expenditure) were already some, and this is your routine for a few days/weeks/months (based on your metabolism) and you are not a bear preparing on a winter (based on actual season), you have a problem.&nbsp;</p>\n<h2>&nbsp;&nbsp;<strong>Okay we got fat - what next?</strong>&nbsp;</h2>\n<p></p>\n<p>During some time of hedonistic eating or few dozens small sins our fat storages are slowly expanded, but nothing is lost yet. It´s time for <strong>leptin</strong>, produced by fat tissue. Basically, more fat we gain, more leptin is generated. It has also receptors in brain and when fat tissue is gaining weight under our skin, our brain starts to give us a good advice – „Okay, this was last bite, we have enough!“ And our appetite is decreased.&nbsp;</p>\n<h2>&nbsp;&nbsp;<strong>When things go wrong...</strong>&nbsp;</h2>\n<p></p>\n<p>We eat, but ghrelin is still high and we are still hungry. Levels of insulin and glucosis are beyond the normal values, but cells are without energy and we are tired (maybe winter´s comming). Fat is too much, leptin is pouring from our ears, but our brain is telling us to eat even a plate.&nbsp;</p>\n<p>Imagine that your phone is ringing. You answer, don´t you? Exspecially, when you see the name of person you know. What happens if he/she starts to call more often? Few times you pick up the phone because you were well-behaved, but if this person is still calling, it starts to bother you. Phone is ringing every moment and you´re loosing your mind. After few calls you stop answer, start ignore it and probably even turn down volume of your phone.&nbsp;</p>\n<p>And this example ilustrates the problem of resistance. If the cells are constantly shooted by „ringing“ of this hormones, they adapt and start ignore these signals. And we´re gaining fat. It´s important to note, if we start solve these problems with maintaining of our diet plan and excercising they´re reversible in the begining (more info in the resources).&nbsp;</p>\n<h2>&nbsp;&nbsp;<strong>Mice with backpacks, without bones... enough internet for today. </strong>&nbsp;</h2>\n<p></p>\n<p>In the beginning of this year a new mechanism of maintaining weight was discovered. First was the question – why people with sedentary lifestyle are prone to gaining weight, even when all hormonal mechanisms mentioned above are working properly? It was hypothesised, there is other mechanism connected with standing. What (or where) is difference between standing and sitting?&nbsp;</p>\n<p>For revealing the truth, mice was used once again. Scientists implanted them weights with different weight under their skin in abdomen or back and give them free amount of food. Surprisingly, mice with weights started to eat less in compare with mice without weights, and subsequently they lost fat. But this wasn´t end. Scientists are scientist because they often ask <em>„why?“</em>. Based on the assumption that osteocytes (type of bone cells) can detect changes of body weight, they started to suspect bones as participants in this mechanism. They depleted osteocytes in mice and effect of loosing weight by carrying weights disappeared. This newly revealed mechanism was called „gravitostat“. As every homeostatic mechanism, it has to have some sensor, and based on this findings, this sensor is located in bones of lower extremities bearing whole body weight. If this mechanism is presented in humans, strained osteocytes in leg bones inform brain about changes of weight and it regulates this changes by negative feedback through maintaining of food intake. So it seems, gravitostat is cooperating with leptin on fat reduction.</p>\n<center>https://steemitimages.com/DQmWCbahNXRyT5iELEwcCZQSGssTzac3aWLMqa5hEWzWJnq/c1cc4718b2a07681a4c4b34a09ef879c32871c5c495c638cb775a6b0143014be.gif</center>\n<p></p>\n<p>So if you have problems with loosing weight, but you eat well and excercise regularly, probably you should think about that what are you doing during the rest of the day. Of course we all have a lot of responsibilities at work or at school, where we have to sit. But maybe isn´t bad idea to use stairs even we have elevator in the building, or make a few steps after lunch. So if you are finished with this article, take a small walk and stimulate your gravitostat. &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>\n<p><br></p>\n<p>Resources:</p>\n<p><a href=\"https://en.wikipedia.org/wiki/Ghrelin\">https://en.wikipedia.org/wiki/Ghrelin</a></p>\n<p><a href=\"https://en.wikipedia.org/wiki/Insulin\">https://en.wikipedia.org/wiki/Insulin</a>&nbsp;</p>\n<p><a href=\"https://en.wikipedia.org/wiki/Leptin\">https://en.wikipedia.org/wiki/Leptin</a>&nbsp;</p>\n<p><a href=\"http://www.pnas.org/content/115/2/427.full\">http://www.pnas.org/content/115/2/427.full</a>&nbsp;</p>\n<p>Reversion of hormone resistance:</p>\n<p><a href=\"https://www.ncbi.nlm.nih.gov/pubmed/17339026\">https://www.ncbi.nlm.nih.gov/pubmed/17339026</a>&nbsp;</p>\n<p><a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/\">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/</a> &nbsp;&nbsp;&nbsp;</p>\n</html>",
      "json_metadata": "{\"tags\":[\"steemstem\",\"steemiteducation\",\"science\",\"health\",\"education\"],\"image\":[\"https://steemitimages.com/DQmQR69huGa2yimNnK3QXTLzuTp4AWCGwdUpnx49hCBsJwK/hngr%20ott%20small.JPG\",\"https://steemitimages.com/DQmZxbK5knNRSi3MzaMGq62cUh3rKdqgQ1ycSC69PVjqaj1/V%C3%BD.JPG\",\"https://steemitimages.com/DQmWCbahNXRyT5iELEwcCZQSGssTzac3aWLMqa5hEWzWJnq/c1cc4718b2a07681a4c4b34a09ef879c32871c5c495c638cb775a6b0143014be.gif\"],\"links\":[\"https://en.wikipedia.org/wiki/Ghrelin\",\"https://en.wikipedia.org/wiki/Insulin\",\"https://en.wikipedia.org/wiki/Leptin\",\"http://www.pnas.org/content/115/2/427.full\",\"https://www.ncbi.nlm.nih.gov/pubmed/17339026\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767170/\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "1db08b4e79f690d48ee9f0e350961ea1dc790334",
  "block": 19210138,
  "trx_in_block": 34,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-22T20:19:24",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "oxygen-and-meeting-the-god",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "4ead0fb7fdc28ef411a6521117800dc65391a346",
  "block": 19210138,
  "trx_in_block": 7,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-22T20:19:24",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "oxygen-and-meeting-the-god",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "d70dacb6761ac7337b90e1a03dcc5e91685841e9",
  "block": 19184345,
  "trx_in_block": 54,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-21T22:49:18",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "nunesso",
      "permlink": "re-antmant-the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health-20180121t132421373z",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "9f70dafb4dbfb010fbd2c61d39a70a33c727804d",
  "block": 19173874,
  "trx_in_block": 6,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-21T14:05:42",
  "op": [
    "custom_json",
    {
      "required_auths": [],
      "required_posting_auths": [
        "antmant"
      ],
      "id": "follow",
      "json": "[\"follow\",{\"follower\":\"antmant\",\"following\":\"steemstem\",\"what\":[\"blog\"]}]"
    }
  ]
}

{
  "trx_id": "d798ad0f8c9998b609135fe9ec9a49ac82fe593d",
  "block": 19173818,
  "trx_in_block": 13,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-21T14:02:54",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "purepinay",
      "permlink": "re-antmant-something-about-me-20180120t063811813z",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "a551fa79bbc87f2fc3299abec89162201ba01a08",
  "block": 19173759,
  "trx_in_block": 2,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-21T13:59:57",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "weight": 0
    }
  ]
}

{
  "trx_id": "fff403e2f007e0733dba4b79402b46a661126150",
  "block": 19173085,
  "trx_in_block": 156,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-21T13:26:15",
  "op": [
    "vote",
    {
      "voter": "jasonbu",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "b8fcd165feb7f04e352b6a9790849a1450feb346",
  "block": 19173047,
  "trx_in_block": 8,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-21T13:24:21",
  "op": [
    "comment",
    {
      "parent_author": "antmant",
      "parent_permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "author": "nunesso",
      "permlink": "re-antmant-the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health-20180121t132421373z",
      "title": "",
      "body": "Congratulations. This post is featured in the week's nunesso's Curation post for the Nutrition and Natural Products industry. You have received a 100% upvote from us.\n\nhttps://steemit.com/natural-products/@nunesso/weekly-nunesso-natural-products-curation-3",
      "json_metadata": "{\"tags\":[\"steemstem\"],\"links\":[\"https://steemit.com/natural-products/@nunesso/weekly-nunesso-natural-products-curation-3\"],\"app\":\"steemit/0.1\"}"
    }
  ]
}

{
  "trx_id": "b2c654d71c0af9954ed9b99e8bca02d47da88b48",
  "block": 19172506,
  "trx_in_block": 14,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-21T12:57:18",
  "op": [
    "vote",
    {
      "voter": "nunesso",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "65d55f8d2c317351d5d5ccd64e230d48b9356003",
  "block": 19156666,
  "trx_in_block": 32,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T23:44:54",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "736efbbc3b27678d42b93d87858483f78be9c8b5",
  "block": 19149338,
  "trx_in_block": 2,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T17:38:27",
  "op": [
    "comment",
    {
      "parent_author": "antmant",
      "parent_permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "author": "steemitboard",
      "permlink": "steemitboard-notify-antmant-20180120t173826000z",
      "title": "",
      "body": "Congratulations @antmant! You have completed some achievement on Steemit and have been rewarded with new badge(s) :\n\n[![](https://steemitimages.com/70x80/http://steemitboard.com/notifications/voted.png)](http://steemitboard.com/@antmant) Award for the number of upvotes received\n[![](https://steemitimages.com/70x80/http://steemitboard.com/notifications/firstvote.png)](http://steemitboard.com/@antmant) You made your First Vote\n[![](https://steemitimages.com/70x80/http://steemitboard.com/notifications/votes.png)](http://steemitboard.com/@antmant) Award for the number of upvotes\n\nClick on any badge to view your own Board of Honor on SteemitBoard.\nFor more information about SteemitBoard, click [here](https://steemit.com/@steemitboard)\n\nIf you no longer want to receive notifications, reply to this comment with the word `STOP`\n\n> By upvoting this notification, you can help all Steemit users. Learn how [here](https://steemit.com/steemitboard/@steemitboard/http-i-cubeupload-com-7ciqeo-png)!",
      "json_metadata": "{\"image\":[\"https://steemitboard.com/img/notifications.png\"]}"
    }
  ]
}

{
  "trx_id": "946cba44bceaa5584ad1e52e3a5b67a7f813e4e3",
  "block": 19143054,
  "trx_in_block": 15,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:24:06",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "hi-steemians-my-name-is-peter-and-this-is-bewise",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "db171ed32df0a0d306ee20648773ab31b132912e",
  "block": 19143054,
  "trx_in_block": 2,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:24:06",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "why-does-the-lsd-trip-last-so-long",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "a115417199b6a48223f97a7839336c4fd127837c",
  "block": 19143053,
  "trx_in_block": 24,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:24:03",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "sexually-deprived-flies-turn-to-booze",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "a8bb7edcde3b72d8289c844a6731af9b172f0596",
  "block": 19143053,
  "trx_in_block": 8,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:24:03",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "your-addicted-brain",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "0abad9c8256c3ed97b7b024911f4ea25fbfcea5a",
  "block": 19143052,
  "trx_in_block": 51,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:24:00",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "how-to-make-dna-in-adobe-after-effects",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "1a53463e4a96aac806718ef3ddad4eb9f681da1b",
  "block": 19143052,
  "trx_in_block": 19,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:24:00",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "how-to-create-a-molecule-protein-structure-in-adobe-illustrator",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "e039333854c350225c38dc39ff4e3d7a423d53f1",
  "block": 19143051,
  "trx_in_block": 56,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:23:57",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "how-to-turn-off-your-chromosomes",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "8e051756d1a6cec1414be8157ca8d75acc51b105",
  "block": 19143051,
  "trx_in_block": 37,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:23:57",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "ancient-viruses-in-your-genome",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "7fab8ee2217873babdc47c96762de366e1d58a84",
  "block": 19143051,
  "trx_in_block": 11,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:23:57",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "genes-and-propability-of-becoming-an-addict",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "0810040efbec48bb96fde824a33dec6343b1401b",
  "block": 19143049,
  "trx_in_block": 44,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:23:51",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "near-death-experience-1-what-is-nde",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "2a58ff0ba3d5b3dfff30558185743e5d1cb18982",
  "block": 19143049,
  "trx_in_block": 26,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:23:51",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "does-the-soul-exist-out-of-body-experience",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "62a5c1f8a1284c605f74875c83e7dfe9958ed7e0",
  "block": 19143047,
  "trx_in_block": 47,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:23:45",
  "op": [
    "vote",
    {
      "voter": "antmant",
      "author": "bewise",
      "permlink": "weirdness-of-your-dreams-and-dying-hallucinations",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "aed54c073af1f77628f5762b39f5a556645698d2",
  "block": 19143042,
  "trx_in_block": 38,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T12:23:30",
  "op": [
    "custom_json",
    {
      "required_auths": [],
      "required_posting_auths": [
        "antmant"
      ],
      "id": "follow",
      "json": "[\"follow\",{\"follower\":\"antmant\",\"following\":\"bewise\",\"what\":[\"blog\"]}]"
    }
  ]
}

{
  "trx_id": "464e08d8e3e48373711415d9ec9dd42908aca326",
  "block": 19141661,
  "trx_in_block": 20,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-20T11:14:24",
  "op": [
    "vote",
    {
      "voter": "bewise",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "weight": 10000
    }
  ]
}

{
  "trx_id": "53bc0a26a2135c1125bd3b1d88c36dc0d9f9e8fd",
  "block": 19118616,
  "trx_in_block": 49,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-19T16:00:48",
  "op": [
    "comment",
    {
      "parent_author": "",
      "parent_permlink": "steemstem",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "title": "The power of our sh*t – how gut microbiota affects our mental health",
      "body": "<html>\n<p></p>\n<center>\n<p>https://steemitimages.com/DQmTd1gPpepSFVLriCDSH7yEUuKMkKHHp5X9GtVYS7bNn5o/V%C3%BDst%C5%99i%C5%BEek2.JPG</p></center>\n<p>We´ve been listening it our whole childhood. „Oh my god don´t eat that sand!, How dirty you are!, Don´t lick that wall! (Am I alone?), Clean your hands!“ But nowadays it seems we have to pay price for higher hygiene and it seems it´s higher incidency different kinds of illneses as allergies but even autism. The best explanation is „Old friend hypothesis“. According this hypothesis evolution our immune system is closely connected with exposuring microbes. It makes sense – know your enemy. So our immunity is like muscle - we have to train it. This aslo explains natural reflex babies to put everything to their mouth. They´re just preparing for a lifetime fight with outer world. &nbsp;&nbsp;</p>\n<h2>From pathogens to close partners – introduction to our microbiota&nbsp;</h2>\n<p></p>\n<p>We´re not alone, even in the empty room. Microbes are everywhere. Pasteur, Koch, Semmelweis, Roux, Behring warned us of the risks posed by pathogenic microbes, aganist which even our trained immunity has just limited resources. Because of the tremedous threat, we noticed them first and we started to fight against them with vaccination or antibiotics. Nevertheless, truth is just a small portion of our surrounding microbes are pathogenic. And for a lot of them, our body is their home. They are living also everywhere, on our skin, our penis and vagina, in the eyes, even in our gut. They don´t asking for attention, just silently doing their work.&nbsp;</p>\n<p>In (and on) our whole body we are carrying from 1 to 2 kilograms of this pets. This is approximately weight of our brain. <strong>But let´s take closer look to our gut</strong>. Every person owns from 500 to 1000 different kinds of microbes in the gut and their number is 10-fold higher than our body cells number. Their genetic information contains 150-fold more genes than ours. But in uterus we´re all sterile. Colonisation of our body starts during birth and while we were travelling through our mother´s vagina, first microbes were „stuck on“ us. As a fingerprint, every person on Earth has got his own uniqe composition of microbiota in our stomach. Uh... okay... but for what? What´s the point of these small occupants? The answer is – something for something. In nature this kind of exchange trade is called <strong>symbiosis</strong>.&nbsp;</p>\n<p>With our teeth we crush it, in our stomach and intestine we dissolve it with powerful enzymes such as amylases, lipases and proteases. The thing is, yield mediated through these enzyme mechanisms is not even close to 100 percent from nutritional potential of our food. Our gut microbiota helps us to digest another portion of energic resources hidden in our food. Bonus is a production of vitamins such as vitamin B and K.&nbsp;</p>\n<p>Every good microbe counts... and for bad is no space. Simple presence of our symbiotic microbes, protects us against settlement pathogenic microbes and this is also reason why we aren´t dying in horrible stomach cramps and diarrheas. Still think dog is your best friend, hooman? &nbsp;</p>\n<center>\n<p>https://steemitimages.com/DQmZ2SApsdJtDpjabRE5ftCUYQqDWrVXNxoiWmarb1C8qTE/GutMicrobeInfographic.png</p></center>\nSource: https://drjockers.com/rebuild-gut-flora-metabolism/\n<p></p>\n<h2><strong>Hello brain, there is gut, how it´s going upstairs?</strong>&nbsp;</h2>\n<p></p>\n<p>Except of these important functions, there is also other interesting function of our gut microbiota, intensively investigated nowadays. <strong>It communicates with our brain.</strong><em> </em>How the hell it´s doing that? In a past years was discovered gut-brain axis or bidirectional communication between brain and gut through neuroendocrine but also immunologic mechanisms. It seems that informations about alternation of gut microbiota are sent through nervus vagus to brain and influence brain development and neuroplasticity. But it´s not just one direction way. External stimuli processed by brain cause releasing of hormones and they are maintaining structure of gut microbiota.</p>\n<center>\n<p>https://steemitimages.com/DQmTwdPMbdWQzkvgMsnT3EcZ99RdWiqAqujWsgo8zs9epuh/Gut-Brain_Axis_large.png</p></center>\n<p>Okay so are you telling me...? Yes. After long introduction, finally the point of the article. For pilot studies of correlation between gut microbiota and mental health were used mice. They stressed these mice (bastards!) through separation from the mother and check their gut microbiota composition. It changed. <strong>But magic continues.</strong> Then they made fecal transplantation (basically they exchange their intestine content) and replaced gut microbiota from stressed mice to mice with normal peaceful conditions, this mice appears much higher level of stress in test and changes were notable also in their brains. But even more, it works aslo in the other way – if stressed mice recieved a gut microbiota from normal mice they were much more restful. Stressed mice just doesn´t give shit anymore. (#minuteofsilenceforthisjoke) &nbsp;&nbsp;</p>\n<h2><strong>What we eat and what we feel&nbsp;</strong></h2>\n<p></p>\n<p>Okay, but what about us? Most recent findings confirm need of exposition of outer microbiota for correct development of our brain, but also for it´s normal development in adulthood. And yes, even in humans was found a connection between altered microbiota and changes of mood and last but not least major depressive disorder, but still more research is needed. After all, most of us are little more complicated than mice.&nbsp;</p>\n<p>We are what we eat. Of course not in a sense of opinions of GMO opponents, but our food significantly affects our gut microbiota composition. A lot of scientists start talk about „psychobiotics“ as a new group of medicines based partially on a food composition, and they believe that in near future this group supports treatment of psychiatric illneses. This is supported by known fact that bad diet is known risk factor of depression, so careful choice of nutrients could be considered as prevent factor. One way is basically to supply microbes externally. A significant effect of probiotics was revealed for improving mood, but also as a prevent factor and reduction of depression. Interesting fact is this effect was observed just in people under 60 years and with no efect in a group of people older than 60 years. And there is lot of possibilities how to boost our gut microbiota through correct diet plan. So yet we aren´t trying exchange our gut microbiota to cure depressions, but is important to note this strange approach is sucessfully used for example in treatment infections of <em>Clostridium difficile</em>, and also, but with much less sucess rate and higher relapses, in treatment ulcerous colitis and there are clinical studies ongoing for many other diseases. Yummy.&nbsp;</p>\n<p>So how we can take care about our microscopic buddies in our gut, what is a good source of probiotics and on the other side what is the damaging factors for them? We will talk about it in a next article! Stay tuned!&nbsp;</p>\n<p>P.S. Mental diseases have too complex nature to explain their incidency only just with altered microbiota. It´s just a small piece in a mosaic in a variability and treatment of this kind of illneses. A lot of good scientific work is needed for making a final decisions from this findings. I you have a problem, seek for a professional help. Today´s medicine is making mile steps. &nbsp;</p>\n<p>References:</p>\n<p>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662178/</p>\n<p>http://www.gutmicrobiotaforhealth.com/en/about-gut-microbiota-info/</p>\n<p>https://www.sciencedirect.com/science/article/pii/S2352289516300509</p>\n<p>https://www.ncbi.nlm.nih.gov/pubmed/27509521&nbsp;</p>\n<p>https://en.wikipedia.org/wiki/Fecal_microbiota_transplant</p>\n</html>",
      "json_metadata": "{\"tags\":[\"steemstem\",\"psychology\",\"science\",\"steemiteducation\",\"health\"],\"image\":[\"https://steemitimages.com/DQmTd1gPpepSFVLriCDSH7yEUuKMkKHHp5X9GtVYS7bNn5o/V%C3%BDst%C5%99i%C5%BEek2.JPG\",\"https://steemitimages.com/DQmZ2SApsdJtDpjabRE5ftCUYQqDWrVXNxoiWmarb1C8qTE/GutMicrobeInfographic.png\",\"https://steemitimages.com/DQmTwdPMbdWQzkvgMsnT3EcZ99RdWiqAqujWsgo8zs9epuh/Gut-Brain_Axis_large.png\"],\"links\":[\"https://drjockers.com/rebuild-gut-flora-metabolism/\",\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662178/\",\"http://www.gutmicrobiotaforhealth.com/en/about-gut-microbiota-info/\",\"https://www.sciencedirect.com/science/article/pii/S2352289516300509\",\"https://www.ncbi.nlm.nih.gov/pubmed/27509521\",\"https://en.wikipedia.org/wiki/Fecal_microbiota_transplant\"],\"app\":\"steemit/0.1\",\"format\":\"html\"}"
    }
  ]
}

{
  "trx_id": "75efb30d63c4760d3075e18817d03c61a97fabb2",
  "block": 19117415,
  "trx_in_block": 56,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2018-01-19T15:00:45",
  "op": [
    "vote",
    {
      "voter": "mikevandergraaf",
      "author": "antmant",
      "permlink": "the-power-of-our-sh-t-how-gut-microbiota-affects-our-mental-health",
      "weight": 10000
    }
  ]
}