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@aakom

58

Exploring the limits of human experience. (A MAP Project)

steemit.com/@aakom
VOTING POWER100.00%
DOWNVOTE POWER100.00%
RESOURCE CREDITS100.00%
REPUTATION PROGRESS92.90%
Net Worth
1.781USD
STEEM
1.533STEEM
SBD
0.618SBD
Own SP
24.065SP

Detailed Balance

STEEM
balance
1.533STEEM
market_balance
0.000STEEM
savings_balance
0.000STEEM
reward_steem_balance
0.000STEEM
STEEM POWER
Own SP
24.065SP
Delegated Out
0.000SP
Delegation In
0.000SP
Effective Power
24.065SP
Reward SP (pending)
1.758SP
SBD
sbd_balance
0.000SBD
sbd_conversions
0.000SBD
sbd_market_balance
0.000SBD
savings_sbd_balance
0.000SBD
reward_sbd_balance
0.618SBD
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Account Info

nameaakom
id512444
rank70,463
reputation4558005063191
created2017-12-20T02:59:30
recovery_accountrycharde
proxyrycharde
post_count306
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last_vote_time2020-07-13T12:01:39
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delayed_votes0
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vesting_shares39144.520471 VESTS
delegated_vesting_shares0.000000 VESTS
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reward_vesting_balance3335.791159 VESTS
vesting_balance0.000 STEEM
vesting_withdraw_rate0.000000 VESTS
next_vesting_withdrawal1969-12-31T23:59:59
withdrawn1612848161202
to_withdraw1612848161202
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savings_withdraw_requests0
last_account_recovery1970-01-01T00:00:00
reset_accountnull
last_owner_update1970-01-01T00:00:00
last_account_update2020-04-28T14:58:12
minedNo
sbd_seconds0
sbd_last_interest_payment2021-02-05T16:42:51
savings_sbd_last_interest_payment1970-01-01T00:00:00
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Withdraw Routes

IncomingOutgoing
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From Date
To Date
ph-supportsent 0.001 STEEM to @aakom
2022/08/16 11:18:51
fromph-support
toaakom
amount0.001 STEEM
memo
Transaction InfoBlock #66851721/Trx 8604adf5ddd03c38c2c537738760ccacbf54068f
View Raw JSON Data
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  "op": [
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2021/03/10 03:17:36
voterafinity4justice
authoraakom
permlinkshattering-cancer-cells-with-resonant-frequencies
weight10000 (100.00%)
Transaction InfoBlock #51874658/Trx be502d9c72a79f33774944f197ade9eaec879d08
View Raw JSON Data
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  "timestamp": "2021-03-10T03:17:36",
  "op": [
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    {
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aakomreceived 0.160 SBD, 0.422 SP author reward for @aakom / online-behaviour-modification-scoring
2021/02/19 01:54:06
authoraakom
permlinkonline-behaviour-modification-scoring
sbd payout0.160 SBD
steem payout0.000 STEEM
vesting payout686.630338 VESTS
Transaction InfoBlock #51335560/Virtual Operation #7
View Raw JSON Data
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      "sbd_payout": "0.160 SBD",
      "steem_payout": "0.000 STEEM",
      "vesting_payout": "686.630338 VESTS"
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}
aakomreceived 0.179 SBD, 0.471 SP author reward for @aakom / i-am-a-plague-doctor-video
2021/02/19 01:47:45
authoraakom
permlinki-am-a-plague-doctor-video
sbd payout0.179 SBD
steem payout0.000 STEEM
vesting payout766.294987 VESTS
Transaction InfoBlock #51335434/Virtual Operation #7
View Raw JSON Data
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      "sbd_payout": "0.179 SBD",
      "steem_payout": "0.000 STEEM",
      "vesting_payout": "766.294987 VESTS"
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  ]
}
2021/02/13 21:40:18
votermaxuv
authoraakom
permlinkonline-behaviour-modification-scoring
weight10000 (100.00%)
Transaction InfoBlock #51188263/Trx 440dfcf82d7c42f940d393e2db5773e18d860a37
View Raw JSON Data
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  "timestamp": "2021-02-13T21:40:18",
  "op": [
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2021/02/13 21:39:54
votermaxuv
authoraakom
permlinki-am-a-plague-doctor-video
weight10000 (100.00%)
Transaction InfoBlock #51188256/Trx 0de2596e7ff2cec1814ccbf888f9e0d1d9f1d629
View Raw JSON Data
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2021/02/13 21:38:21
votermaxuvd
authoraakom
permlinkonline-behaviour-modification-scoring
weight1200 (12.00%)
Transaction InfoBlock #51188226/Trx f696432c273b7585db3f9f3c84ee76f4847bf2c6
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2021/02/13 21:38:06
votermaxuvd
authoraakom
permlinki-am-a-plague-doctor-video
weight1200 (12.00%)
Transaction InfoBlock #51188221/Trx 60b49db4861b2b0da327e60bdb734351e69d3f23
View Raw JSON Data
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}
2021/02/13 21:37:27
votermaxuve
authoraakom
permlinkonline-behaviour-modification-scoring
weight10000 (100.00%)
Transaction InfoBlock #51188208/Trx 74be77b8ee3efde04f743425b16f4f6b679ebe32
View Raw JSON Data
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  "op": [
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2021/02/13 21:37:12
votermaxuve
authoraakom
permlinki-am-a-plague-doctor-video
weight10000 (100.00%)
Transaction InfoBlock #51188203/Trx c486e5042ce8026795f1f3de5aba8643f5f6fe86
View Raw JSON Data
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2021/02/13 11:09:57
votercrismali
authoraakom
permlinkonline-behaviour-modification-scoring
weight-1000 (-10.00%)
Transaction InfoBlock #51175797/Trx 345c0fb738f5deb85f3dfd36b9949d96c4720dea
View Raw JSON Data
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  "op": [
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aakomreceived 0.127 SBD, 0.526 SP author reward for @aakom / shattering-cancer-cells-with-resonant-frequencies
2021/02/12 16:54:09
authoraakom
permlinkshattering-cancer-cells-with-resonant-frequencies
sbd payout0.127 SBD
steem payout0.000 STEEM
vesting payout856.020406 VESTS
Transaction InfoBlock #51154214/Virtual Operation #7
View Raw JSON Data
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  "op": [
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    {
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      "permlink": "shattering-cancer-cells-with-resonant-frequencies",
      "sbd_payout": "0.127 SBD",
      "steem_payout": "0.000 STEEM",
      "vesting_payout": "856.020406 VESTS"
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}
aakomreceived 0.152 SBD, 0.631 SP author reward for @aakom / synthetic-telepathy-experiment-tests-for-zombies
2021/02/12 16:47:03
authoraakom
permlinksynthetic-telepathy-experiment-tests-for-zombies
sbd payout0.152 SBD
steem payout0.000 STEEM
vesting payout1026.845428 VESTS
Transaction InfoBlock #51154072/Virtual Operation #7
View Raw JSON Data
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  "op": [
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    {
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      "permlink": "synthetic-telepathy-experiment-tests-for-zombies",
      "sbd_payout": "0.152 SBD",
      "steem_payout": "0.000 STEEM",
      "vesting_payout": "1026.845428 VESTS"
    }
  ]
}
2021/02/12 12:25:33
voteraccelerator
authoraakom
permlinkonline-behaviour-modification-scoring
weight10000 (100.00%)
Transaction InfoBlock #51148902/Trx e0967f8fc576fa4303445a1122cd91e2dacdb85d
View Raw JSON Data
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  "op": [
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}
2021/02/12 12:23:06
voteraccelerator
authoraakom
permlinki-am-a-plague-doctor-video
weight10000 (100.00%)
Transaction InfoBlock #51148854/Trx 87c1cc0039a407ac5cf18c88298b72409fe83932
View Raw JSON Data
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  "op": [
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      "author": "aakom",
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      "weight": 10000
    }
  ]
}
2021/02/12 10:31:33
voterbrismser
authoraakom
permlinkonline-behaviour-modification-scoring
weight-1000 (-10.00%)
Transaction InfoBlock #51146652/Trx 19796fc6a0a948894ea811a5858d7a358d8abbd0
View Raw JSON Data
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  "timestamp": "2021-02-12T10:31:33",
  "op": [
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      "author": "aakom",
      "permlink": "online-behaviour-modification-scoring",
      "weight": -1000
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}
2021/02/12 02:08:30
votersteembasicincome
authoraakom
permlinkonline-behaviour-modification-scoring
weight3492 (34.92%)
Transaction InfoBlock #51136715/Trx 487996ebe5bc3a6baa3e2cfc6485b99366a58552
View Raw JSON Data
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  "op": [
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2021/02/12 01:59:03
voterinto.software
authoraakom
permlinkshattering-cancer-cells-with-resonant-frequencies
weight10000 (100.00%)
Transaction InfoBlock #51136528/Trx 67d6ec36d07997072cb3feb331ca94990924d2c1
View Raw JSON Data
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  "op": [
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2021/02/12 01:54:06
parent author
parent permlinktechnocracy
authoraakom
permlinkonline-behaviour-modification-scoring
titleOnline Behaviour Modification Scoring
bodyThe technocratic pathocracy keeps marching forward as the proles are driven to distraction by their addiction to their phones. [IMF Calls For Internet Search History To Be Linked To Your Credit Score](https://www.technocracy.news/imf-calls-for-internet-search-history-to-be-linked-to-your-credit-score/) and [IMF Calls for Credit Score to be Tied to Internet Search History](https://realitycircuit.com/2020/12/23/imf-calls-for-credit-score-to-be-tied-to-internet-search-history/). The key document is [Financial Intermediation and Technology: What’s Old, What’s New?](https://www.imf.org/en/Publications/WP/Issues/2020/08/07/Financial-Intermediation-and-Technology-Whats-Old-Whats-New-49624) and the shorter [blog post](https://blogs.imf.org/2020/12/17/what-is-really-new-in-fintech/) based on the longer paper. It is sometimes hard to see the real intentions behind a veil of banker-speak. >The most transformative information innovation is the increase in use of new types of data coming from the digital footprint of customers’ various online activities—mainly for credit-worthiness analysis. What does that really mean? Think social credit scoring. Think soft prison. You may never even notice, until you're stopped from doing something. What this also means is that if you hide your online behaviour, you become a non-person. You must obey both in terms of behaviour *and* in allowing that behaviour to be tracked, logged and confirmed.
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      "body": "The technocratic pathocracy keeps marching forward as the proles are driven to distraction by their addiction to their phones.\n\n[IMF Calls For Internet Search History To Be Linked To Your Credit Score](https://www.technocracy.news/imf-calls-for-internet-search-history-to-be-linked-to-your-credit-score/) and [IMF Calls for Credit Score to be Tied to Internet Search History](https://realitycircuit.com/2020/12/23/imf-calls-for-credit-score-to-be-tied-to-internet-search-history/).\n\nThe key document is [Financial Intermediation and Technology: What’s Old, What’s New?](https://www.imf.org/en/Publications/WP/Issues/2020/08/07/Financial-Intermediation-and-Technology-Whats-Old-Whats-New-49624) and the shorter [blog post](https://blogs.imf.org/2020/12/17/what-is-really-new-in-fintech/) based on the longer paper.\n\nIt is sometimes hard to see the real intentions behind a veil of banker-speak.\n\n>The most transformative information innovation is the increase in use of new types of data coming from the digital footprint of customers’ various online activities—mainly for credit-worthiness analysis.\n\nWhat does that really mean?\n\nThink social credit scoring.\n\nThink soft prison.\n\nYou may never even notice, until you're stopped from doing something.\n\nWhat this also means is that if you hide your online behaviour, you become a non-person. You must obey both in terms of behaviour *and* in allowing that behaviour to be tracked, logged and confirmed.",
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2021/02/12 01:53:12
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aakompublished a new post: i-am-a-plague-doctor-video
2021/02/12 01:47:45
parent author
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authoraakom
permlinki-am-a-plague-doctor-video
titleI Am A Plague Doctor Video
bodyAn interesting short video. <center>https://youtu.be/Nw0wGaVCWiQ</center> Useful to read this too: [Biological Warfare at the 1346 Siege of Caffa](https://wwwnc.cdc.gov/eid/article/8/9/01-0536_article). Although medics may not have had a name for the vector of the disease, they did know aspects of its transmission, hence the plague doctor beak masks filled with herbs to "cleanse" the foul stench in the air. Other videos [here](https://youtu.be/z3P0kTcM8iw) and [here](https://youtu.be/m5q-PIN3KSE), with various levels of annoyance. This is a much longer and better [documentary](https://youtu.be/HPe6BgzHWY0), with a focus on the plague in London, 1665. A year later, the city was cleansed in an inferno, that also killed the infecting rats and fleas, that were, astonishingly, not considered the primary source of the infections. Notice what a REAL pandemic looks like.
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      "body": "An interesting short video.\n\n<center>https://youtu.be/Nw0wGaVCWiQ</center>\n\nUseful to read this too: [Biological Warfare at the 1346 Siege of Caffa](https://wwwnc.cdc.gov/eid/article/8/9/01-0536_article).\n\nAlthough medics may not have had a name for the vector of the disease, they did know aspects of its transmission, hence the plague doctor beak masks filled with herbs to \"cleanse\" the foul stench in the air.\n\nOther videos [here](https://youtu.be/z3P0kTcM8iw) and [here](https://youtu.be/m5q-PIN3KSE), with various levels of annoyance.\n\nThis is a much longer and better [documentary](https://youtu.be/HPe6BgzHWY0), with a focus on the plague in London, 1665. A year later, the city was cleansed in an inferno, that also killed the infecting rats and fleas, that were, astonishingly, not considered the primary source of the infections.\n\nNotice what a REAL pandemic looks like.",
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2021/02/07 01:04:51
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2021/02/06 23:54:33
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2021/02/06 22:49:54
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2021/02/06 15:22:09
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2021/02/05 21:11:57
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2021/02/05 17:36:21
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2021/02/05 17:36:21
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2021/02/05 17:36:21
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2021/02/05 17:35:24
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2021/02/05 17:08:00
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2021/02/05 17:07:33
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2021/02/05 16:57:39
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2021/02/05 16:57:36
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2021/02/05 16:56:42
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2021/02/05 16:54:09
parent author
parent permlinkscience
authoraakom
permlinkshattering-cancer-cells-with-resonant-frequencies
titleShattering cancer cells with resonant frequencies
bodyThe work of Royal Rife lives on... has taken some 100 years to get back to this line of research. <center>https://youtu.be/1w0_kazbb_U</center> Frequencies can heal and they can destroy, whether you perceive them or not. One amusing thing, I hadn't noticed before. >NOTE FROM TED: Please do not look to this talk for medical advice. We've flagged this talk, which was filmed at a TEDx event, because it appears to fall outside TEDx's content guidelines. Resonant Frequency Therapy has not been proven effective by scientific research. then at the foot, TED's usual puff piece. >In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. No hypocrisy there, then! TED Talks can be amusing and a quick way to delve into a new topic, but it is deeply entrenched in mainstream propaganda. A list of all "banned TED talks" makes a fascinating collection of the sciences moving too close to private corporate knowledge. Here is an application of the same idea to a [recent virus](https://www.oatext.com/introducing-covid-19-as-an-evolutionary-metabolic-infectious-disease-emid-the-prime-cause-and-representing-alternative-treatment-for-covid-19-sars-cov-2.php).
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      "body": "The work of Royal Rife lives on... has taken some 100 years to get back to this line of research.\n\n<center>https://youtu.be/1w0_kazbb_U</center>\n\nFrequencies can heal and they can destroy, whether you perceive them or not.\n\nOne amusing thing, I hadn't noticed before.\n\n>NOTE FROM TED: Please do not look to this talk for medical advice. We've flagged this talk, which was filmed at a TEDx event, because it appears to fall outside TEDx's content guidelines. Resonant Frequency Therapy has not been proven effective by scientific research.\n\nthen at the foot, TED's usual puff piece.\n\n>In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group.\n\nNo hypocrisy there, then! TED Talks can be amusing and a quick way to delve into a new topic, but it is deeply entrenched in mainstream propaganda. A list of all \"banned TED talks\" makes a fascinating collection of the sciences moving too close to private corporate knowledge.\n\nHere is an application of the same idea to a [recent virus](https://www.oatext.com/introducing-covid-19-as-an-evolutionary-metabolic-infectious-disease-emid-the-prime-cause-and-representing-alternative-treatment-for-covid-19-sars-cov-2.php).",
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2021/02/05 16:52:33
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2021/02/05 16:52:30
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2021/02/05 16:52:15
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2021/02/05 16:49:30
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2021/02/05 16:47:03
parent author
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authoraakom
permlinksynthetic-telepathy-experiment-tests-for-zombies
titleSynthetic Telepathy Experiment Tests for Zombies
bodyThis paper is from 2014, but I cam across it from this [recent article](https://collective-spark.xyz/study-humans-can-communicate-from-brain-to-brain-telepathy/). What caught my eye was the gush about human "telepathy" - I used the word myself - but this is no such thing. The research is about creating a synthetic brain-to-brain interface (BBI): [A Direct Brain-to-Brain Interface in Humans](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111332). Indeed, reading the paper, even the word "communication" is tenuous, in that the sender and receiver do not actually exchange any information; they make no decisions. The receiver is actually just a zombie "following orders" from his transcranial magnetic stimulation (TMS) device that delivers its "orders" through a magnetic field. The receiver is merely reacting to the magnetic field and has no knowledge of the consequences of his actions. The experiment was partly funded by the US Army Research Office, so we can see where this is going: either human-to-zombie or human-to-robot communications, thereby using the judgments of a human and the disposable hardware of, say, a combatant out in a field of fire. <center>https://i.imgur.com/f2JiCA7.png</center> Not quite "telepathy". If you look at the data, you'll also see how incompetent some of the participants were! One other thought: you know the unwarranted belief that magnetic fields have no effect on humans? So how does TMS work? How does MEG work? Would you like rogue synthetic magnetic fields to decide your actions for you? --- <sub>image: [plosone CC](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111332)</sub>
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      "permlink": "synthetic-telepathy-experiment-tests-for-zombies",
      "title": "Synthetic Telepathy Experiment Tests for Zombies",
      "body": "This paper is from 2014, but I cam across it from this [recent article](https://collective-spark.xyz/study-humans-can-communicate-from-brain-to-brain-telepathy/). What caught my eye was the gush about human \"telepathy\" - I used the word myself - but this is no such thing. The research is about creating a synthetic brain-to-brain interface (BBI): [A Direct Brain-to-Brain Interface in Humans](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111332). \n\nIndeed, reading the paper, even the word \"communication\" is tenuous, in that the sender and receiver do not actually exchange any information; they make no decisions. The receiver is actually just a zombie \"following orders\" from his transcranial magnetic stimulation (TMS) device that delivers its \"orders\" through a magnetic field. The receiver is merely reacting to the magnetic field and has no knowledge of the consequences of his actions.\n\nThe experiment was partly funded by the US Army Research Office, so we can see where this is going: either human-to-zombie or human-to-robot communications, thereby using the judgments of a human and the disposable hardware of, say, a combatant out in a field of fire.\n\n<center>https://i.imgur.com/f2JiCA7.png</center>\n\nNot quite \"telepathy\".\n\nIf you look at the data, you'll also see how incompetent some of the participants were! \n\nOne other thought: you know the unwarranted belief that magnetic fields have no effect on humans? So how does TMS work? How does MEG work? Would you like rogue synthetic magnetic fields to decide your actions for you?\n\n---\n\n<sub>image: [plosone CC](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111332)</sub>",
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aakomblockchain operation: limit order create
2021/02/05 16:42:51
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aakombought 1.532 STEEM for 0.117 SBD from @quicktrades
2021/02/05 16:42:51
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2021/02/05 16:41:27
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aakomclaimed reward balance: 0.031 STEEM, 0.117 SBD, 0.908 SP
2021/02/05 16:39:45
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2021/01/03 02:59:15
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2020/12/28 06:21:00
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2020/12/28 02:51:21
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2020/12/27 03:06:12
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2020/12/27 03:04:30
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2020/12/27 03:04:27
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2020/12/27 03:04:18
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2020/12/27 03:04:12
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executive-boardsent 0.001 STEEM to @aakom- "❗ Hello aakom, great that you are using the STEEM blockchain. The Executive Board hereby invites you to https://discord.gg/KyBbmhh where you will get some insider infos on how you will earn the most c..."
2020/12/27 03:01:06
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amount0.001 STEEM
memo❗ Hello aakom, great that you are using the STEEM blockchain. The Executive Board hereby invites you to https://discord.gg/KyBbmhh where you will get some insider infos on how you will earn the most coins. It's easy, just follow the instructions. Warm regards, The Executive Board.
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2020/12/27 02:59:15
parent author
parent permlinkhealth
authoraakom
permlinkchronic-fatigue-syndrome-is-not-psychosomatic-probably-epigenetic
titleChronic Fatigue Syndrome is not Psychosomatic, Probably Epigenetic
bodyMolecular biologist Warren Tate, Otago University Emeritus Professor, has recently published two papers that shed some light on the condition known as Myalgic Encephalamyelitis (ME), also known as Chronic Fatigue Syndrome (the preferred term is now ME/CFS). His daughter developed ME at the age of 14 and, as in so many so-called auto-immune or psychosomatic conditions, when professor Tate did a search of the medical literature he found precious little in the way of solid information. <center>https://i.imgur.com/qyBqUaf.jpg</center> There are other conditions where the collective signal from the medical cartels seems to be, "We don't know and we don't care!" So, if you suffer from such a condition, then I will show you how to find out as much as you can so that you can either heal yourself or have a solid foundation to request further medical investigations. OK, let's move on. [A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction](https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02533-3). >Of particular relevance to the core symptoms of fatigue and post-exertional malaise experienced in ME/CFS, a proportion of the identified proteins in the ME/CFS groups were involved in mitochondrial function, oxidative phosphorylation, electron transport chain complexes, and redox regulation. A significant number were also involved in previously implicated disturbances in ME/CFS, such as the immune inflammatory response, DNA methylation, apoptosis and proteasome activation. Sounds to me like a reaction to "medication". Always, always, think back to when your own symptoms started and recall any medications taken within, say, 3 months previously. The Conclusions in the Abstract go on to say: >The results from this study support a model of deficient ATP production in ME/CFS, compensated for by upregulation of immediate pathways upstream of Complex V [ATP synthase] that would suggest an elevation of oxidative stress. Further on: >Flu-like and respiratory symptoms are common, and for a large subset of sufferers, the onset of the illness is sudden and is preceded by an acute viral-like infectious period. No mention of the "medication" taken during such an illness. Never blame the drugs. This is a guided tour of a devastating landscape of chronic illnesses. This will take many articles to pick through the rubble. As always, medical researchers are taught to look for a "pathogen" - even an invented one - rather than look at the most obvious and causal trigger. The word "pathogen" means a "creator of disease", combining the Greek *pathos* amd *genesis*; indeed "pathos" also means "suffering" or, in literature and rhetoric, the more general meaning of "eliciting emotions". Note that in the Wikipedia entry for [Pathogen](https://en.wikipedia.org/wiki/Pathogen) the causative agent is always some organism - other causes such as toxins (like drugs) are not included. This means that the "hunt for a pathogen" is invariably a search for some nefarious organism - while the real culprit is often left unmolested. Don't get me wrong, this is nothing against Warren Tate, as his research is interesting, else I wouldn't bother writing about it, but is an observation on the intellectual culture of medicine whereby research is hemmed in by very real ideological boxes. I shall go into more details in another post as medspeak is an interesting mixture of precision and obfuscation. Tate's observations about DNA methylation lead into his second paper: [Changes in DNA methylation profiles of myalgic encephalomyelitis/chronic fatigue syndrome patients reflect systemic dysfunctions](https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-020-00960-z). >Major differences were identified in the DNA methylation patterns of ME/CFS patients that clearly distinguished them from the healthy controls. [...] Within the enriched functional immune, metabolic and neurological pathways, a number of enriched neurotransmitter and neuropeptide reactome pathways highlighted a disturbed neurological pathophysiology within the patient group. So, what is DNA methylation? The article says: >DNA methylation is the best understood epigenetic modification where the addition of a methyl group to the cytosine base of DNA is associated with changes in gene expression without altering the genomic code itself. This biological interface between an individual’s environment and the regulation of their genome can provide insights into an individual’s disease activity. Read that last sentence again... slowly. *Your environment can regulate your gene expression!* Your environment includes everything that interacts with your body - air, food, drugs, water - including those molecules that can effect an epigenetic change. Such changes do not affect your DNA directly but they can switch some genes on and off. Think of a computer code where you can "comment out" certain lines so that they are still within the code but they are not processed - that's an epi(genetic)code change. Such genes are the instruction-sets to create certain proteins, so that switching them on when they should be off, or switching them off when they should be on, can create a wealth of problems, from mild to catastrophic, depending on the gene. You may now be wondering what DNA methylation and epigenetics have to do with prescribed drugs? Take a look at this website: [The Human Epigenetic Drug Database (HEDD)](http://hedds.org/index.jsp). >The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level. The site includes data on clinical trials and also novel uses for some existing drugs, which means... *some existing drugs already cause epigenetic changes!* In theory: >Epigenetic enzymes ‘write’ the DNA methylation and histone code and ‘erase’ the histone code. The recognition of these changes by adaptor proteins ‘read’ the histone code. Working in concert, three classes of epigenetic proteins (‘writers’, ‘erasers’ and ‘readers’) function to determine whether genes are turned on or off, and the deregulation of these processes plays a central part in several diseases. [[source](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199199/)] However, if researchers will never admit that existing prescription drugs may well be causing epigenetic changes, then that "reverse step" will never be developed because it isn't even an option on the table. Remember that drugs are not considered pathogens, hence cannot be the cause of so much misery around the world. Think again.
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      "body": "Molecular biologist Warren Tate, Otago University Emeritus Professor, has recently published two papers that shed some light on the condition known as Myalgic Encephalamyelitis (ME), also known as Chronic Fatigue Syndrome (the preferred term is now ME/CFS). \n\nHis daughter developed ME at the age of 14 and, as in so many so-called auto-immune or psychosomatic conditions, when professor Tate did a search of the medical literature he found precious little in the way of solid information. \n\n<center>https://i.imgur.com/qyBqUaf.jpg</center>\n\nThere are other conditions where the collective signal from the medical cartels seems to be, \"We don't know and we don't care!\" So, if you suffer from such a condition, then I will show you how to find out as much as you can so that you can either heal yourself or have a solid foundation to request further medical investigations. OK, let's move on.\n\n[A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction](https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02533-3).\n\n>Of particular relevance to the core symptoms of fatigue and post-exertional malaise experienced in ME/CFS, a proportion of the identified proteins in the ME/CFS groups were involved in mitochondrial function, oxidative phosphorylation, electron transport chain complexes, and redox regulation. A significant number were also involved in previously implicated disturbances in ME/CFS, such as the immune inflammatory response, DNA methylation, apoptosis and proteasome activation.\n\nSounds to me like a reaction to \"medication\". Always, always, think back to when your own symptoms started and recall any medications taken within, say, 3 months previously.\n\nThe Conclusions in the Abstract go on to say:\n\n>The results from this study support a model of deficient ATP production in ME/CFS, compensated for by upregulation of immediate pathways upstream of Complex V [ATP synthase] that would suggest an elevation of oxidative stress.\n\nFurther on:\n\n>Flu-like and respiratory symptoms are common, and for a large subset of sufferers, the onset of the illness is sudden and is preceded by an acute viral-like infectious period.\n\nNo mention of the \"medication\" taken during such an illness. Never blame the drugs. This is a guided tour of a devastating landscape of chronic illnesses. This will take many articles to pick through the rubble.\n\nAs always, medical researchers are taught to look for a \"pathogen\" - even an invented one - rather than look at the most obvious and causal trigger. The word \"pathogen\" means a \"creator of disease\", combining the Greek *pathos* amd *genesis*; indeed \"pathos\" also means \"suffering\" or, in literature and rhetoric, the more general meaning of \"eliciting emotions\". Note that in the Wikipedia entry for [Pathogen](https://en.wikipedia.org/wiki/Pathogen) the causative agent is always some organism - other causes such as toxins (like drugs) are not included. This means that the \"hunt for a pathogen\" is invariably a search for some nefarious organism - while the real culprit is often left unmolested.\n\nDon't get me wrong, this is nothing against Warren Tate, as his research is interesting, else I wouldn't bother writing about it, but is an observation on the intellectual culture of medicine whereby research is hemmed in by very real ideological boxes. I shall go into more details in another post as medspeak is an interesting mixture of precision and obfuscation. \n\nTate's observations about DNA methylation lead into his second paper: [Changes in DNA methylation profiles of myalgic encephalomyelitis/chronic fatigue syndrome patients reflect systemic dysfunctions](https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-020-00960-z).\n\n>Major differences were identified in the DNA methylation patterns of ME/CFS patients that clearly distinguished them from the healthy controls. [...] Within the enriched functional immune, metabolic and neurological pathways, a number of enriched neurotransmitter and neuropeptide reactome pathways highlighted a disturbed neurological pathophysiology within the patient group.\n\nSo, what is DNA methylation? The article says:\n\n>DNA methylation is the best understood epigenetic modification where the addition of a methyl group to the cytosine base of DNA is associated with changes in gene expression without altering the genomic code itself. This biological interface between an individual’s environment and the regulation of their genome can provide insights into an individual’s disease activity.\n\nRead that last sentence again... slowly. *Your environment can regulate your gene expression!*\n\nYour environment includes everything that interacts with your body - air, food, drugs, water - including those molecules that can effect an epigenetic change. Such changes do not affect your DNA directly but they can switch some genes on and off. Think of a computer code where you can \"comment out\" certain lines so that they are still within the code but they are not processed - that's an epi(genetic)code change. Such genes are the instruction-sets to create certain proteins, so that switching them on when they should be off, or switching them off when they should be on, can create a wealth of problems, from mild to catastrophic, depending on the gene.\n\nYou may now be wondering what DNA methylation and epigenetics have to do with prescribed drugs? Take a look at this website: [The Human Epigenetic Drug Database (HEDD)](http://hedds.org/index.jsp).\n\n>The Human Epigenetic Drug Database (HEDD) is a comprehensive web-based database for epigenetic drugs, which focuses on the storage and integration of epigenetic drug datasets that were obtained from laboratory experiments that is essential for understanding the mechanism of action of these epigenetic drugs at a systematic level.\n\nThe site includes data on clinical trials and also novel uses for some existing drugs, which means... *some existing drugs already cause epigenetic changes!*\n\nIn theory:\n\n>Epigenetic enzymes ‘write’ the DNA methylation and histone code and ‘erase’ the histone code. The recognition of these changes by adaptor proteins ‘read’ the histone code. Working in concert, three classes of epigenetic proteins (‘writers’, ‘erasers’ and ‘readers’) function to determine whether genes are turned on or off, and the deregulation of these processes plays a central part in several diseases. [[source](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199199/)]\n\nHowever, if researchers will never admit that existing prescription drugs may well be causing epigenetic changes, then that \"reverse step\" will never be developed because it isn't even an option on the table. Remember that drugs are not considered pathogens, hence cannot be the cause of so much misery around the world.\n\nThink again.",
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2020/07/20 11:56:00
curatoraakom
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aakomclaimed reward balance: 2.170 SP
2020/07/16 03:53:36
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2020/07/13 12:01:39
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2020/07/06 07:55:39
curatoraakom
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2020/06/30 19:38:45
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2020/06/29 14:36:00
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2020/06/29 08:01:45
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2020/06/23 19:38:45
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2020/06/22 14:41:42
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2020/06/22 08:52:09
curatoraakom
reward19.468249 VESTS
comment authoraccelerator
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aakomreceived 63.699 STEEM from power down installment (76.272 SP)
2020/06/16 19:38:45
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  "timestamp": "2020-06-16T19:38:45",
  "op": [
    "fill_vesting_withdraw",
    {
      "from_account": "aakom",
      "to_account": "aakom",
      "withdrawn": "124065.243170 VESTS",
      "deposited": "63.699 STEEM"
    }
  ]
}
2020/06/16 18:58:42
curatoraakom
reward13.634329 VESTS
comment authorsteemchiller
comment permlinksteemworld-update-new-tool-for-managing-account-authorities
Transaction InfoBlock #44307183/Virtual Operation #202
View Raw JSON Data
{
  "trx_id": "0000000000000000000000000000000000000000",
  "block": 44307183,
  "trx_in_block": 4294967295,
  "op_in_trx": 0,
  "virtual_op": 202,
  "timestamp": "2020-06-16T18:58:42",
  "op": [
    "curation_reward",
    {
      "curator": "aakom",
      "reward": "13.634329 VESTS",
      "comment_author": "steemchiller",
      "comment_permlink": "steemworld-update-new-tool-for-managing-account-authorities"
    }
  ]
}
2020/06/16 09:48:36
curatoraakom
reward31.165193 VESTS
comment authoraccelerator
comment permlinkmapr-and-crypto-news-stock-to-flow-model-btc-9-june-2020
Transaction InfoBlock #44296309/Virtual Operation #23
View Raw JSON Data
{
  "trx_id": "0000000000000000000000000000000000000000",
  "block": 44296309,
  "trx_in_block": 4294967295,
  "op_in_trx": 0,
  "virtual_op": 23,
  "timestamp": "2020-06-16T09:48:36",
  "op": [
    "curation_reward",
    {
      "curator": "aakom",
      "reward": "31.165193 VESTS",
      "comment_author": "accelerator",
      "comment_permlink": "mapr-and-crypto-news-stock-to-flow-model-btc-9-june-2020"
    }
  ]
}
2020/06/15 08:58:03
voteraakom
authoraccelerator
permlinkmap-rewarder-mapr-payouts-to-delegators-and-price-increase-for-token-holders-for-15-june-2020-18-3-apr
weight10000 (100.00%)
Transaction InfoBlock #44266851/Trx 22629b5e10265022ef85781a99f0af38cde0ce8c
View Raw JSON Data
{
  "trx_id": "22629b5e10265022ef85781a99f0af38cde0ce8c",
  "block": 44266851,
  "trx_in_block": 0,
  "op_in_trx": 0,
  "virtual_op": 0,
  "timestamp": "2020-06-15T08:58:03",
  "op": [
    "vote",
    {
      "voter": "aakom",
      "author": "accelerator",
      "permlink": "map-rewarder-mapr-payouts-to-delegators-and-price-increase-for-token-holders-for-15-june-2020-18-3-apr",
      "weight": 10000
    }
  ]
}

Account Metadata

POSTING JSON METADATA
profile{"profile_image":"https://i.imgur.com/IA44GhX.png","name":"AAKOM","about":"Exploring the limits of human experience. (A MAP Project)","website":"http://bit.ly/AAKOMJOIN","location":"Join the community ==>>"}
JSON METADATA
profile{"profile_image":"https://i.imgur.com/IA44GhX.png","name":"AAKOM","about":"Exploring the limits of human experience. (A MAP Project)","website":"http://bit.ly/AAKOMJOIN","location":"Join the community ==>>"}
{
  "posting_json_metadata": {
    "profile": {
      "profile_image": "https://i.imgur.com/IA44GhX.png",
      "name": "AAKOM",
      "about": "Exploring the limits of human experience. (A MAP Project)",
      "website": "http://bit.ly/AAKOMJOIN",
      "location": "Join the community ==>>"
    }
  },
  "json_metadata": {
    "profile": {
      "profile_image": "https://i.imgur.com/IA44GhX.png",
      "name": "AAKOM",
      "about": "Exploring the limits of human experience. (A MAP Project)",
      "website": "http://bit.ly/AAKOMJOIN",
      "location": "Join the community ==>>"
    }
  }
}

Auth Keys

Owner
Single Signature
Public Keys
STM8YNjEqvW19hsmuRhajmeZdC489MimmTey6Vy58gGdrUATuvfgi1/1
Active
Single Signature
Public Keys
STM8Ccysq2AHuQnY2NgLnmhzyj1gbjLyDvujDpZPQGhtungZZqG4B1/1
Posting
Single Signature
Public Keys
STM7JSNkr863tq286Qhr7njDmtVPVD9Du6pEggdn7ysoxiRXkmEHQ1/1
Memo
STM8fXS6BpkxNyqCbnFd7jbYayX79WnR6hhsKd5YHnZLPggyUKYxN
{
  "owner": {
    "weight_threshold": 1,
    "account_auths": [],
    "key_auths": [
      [
        "STM8YNjEqvW19hsmuRhajmeZdC489MimmTey6Vy58gGdrUATuvfgi",
        1
      ]
    ]
  },
  "active": {
    "weight_threshold": 1,
    "account_auths": [],
    "key_auths": [
      [
        "STM8Ccysq2AHuQnY2NgLnmhzyj1gbjLyDvujDpZPQGhtungZZqG4B",
        1
      ]
    ]
  },
  "posting": {
    "weight_threshold": 1,
    "account_auths": [
      [
        "dlike.app",
        1
      ],
      [
        "rewarding",
        1
      ],
      [
        "smartsteem",
        1
      ],
      [
        "steemauto",
        1
      ],
      [
        "steempeak.app",
        1
      ],
      [
        "steemqa-io",
        1
      ]
    ],
    "key_auths": [
      [
        "STM7JSNkr863tq286Qhr7njDmtVPVD9Du6pEggdn7ysoxiRXkmEHQ",
        1
      ]
    ]
  },
  "memo": "STM8fXS6BpkxNyqCbnFd7jbYayX79WnR6hhsKd5YHnZLPggyUKYxN"
}

Witness Votes

0 / 30
No active witness votes (Proxied to @rycharde).
[]